The vitamin D receptor (VDR) is found in nearly all, if not all, cells in the body. The enzyme
that produces the active metabolite of vitamin D and ligand for VDR, namely CYP27B1 …

Various epidemiological studies have shown an aetiological link between vitamin D
deficiency and cancer incidence. The active metabolite of vitamin D, 1, 25-dihydroxyvitamin …

BACKGROUND/AIMS: 1, 25-dihydroxyvitamin-D is involved in immunomodulation.
Expression of vitamin-D receptors in hepatocytes suggests its role in hepatocellular injury …

Reactive oxygen species (ROS) are important endogenous etiological agents for DNA
damage, and ROS perform critical signaling functions in apoptosis, stress responses and …

A complex of two S100 EF-hand calcium-binding proteins S100A8/A9 induces apoptosis in
various cells, especially tumor cells. Using several cell lines, we have shown that …

[Frontiers in Bioscience 10, 2723-2749, September 1, 2005] 2723 VITAMIN D AND
CANCER: AN UPDATE OF IN VITRO AND IN VIVO DATA Pal Page 1 [Frontiers in …

The negative association of the latitude where people live and the incidence of non
cutaneous cancer in that population in North America have been demonstrated in many …

Cancer is a heterogeneous set of diseases characterized by the rewiring of cellular
signaling and the reprogramming of metabolic pathways to sustain growth and proliferation …

Vitamin D3 has emerged as an important regulator of the immune system. With metabolic
enzymes for vitamin D3 activation and vitamin D receptors (VDR) now identified in a variety …

Recent studies suggest that growth inhibition by 1, 25-dihydroxyvitamin D 3 represents an
innovative approach to ovarian cancer therapy. To understand the molecular mechanism of …