Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

Following a diagnosis of breast cancer, the most immediate challenges in patient
management are the determination of prognosis and identification of the most appropriate …

As the culprit behind most cancer-related deaths, metastasis is the ultimate challenge in our
effort to fight cancer as a life-threatening disease. The explosive growth of metastasis …

Stress induced by the accumulation of unfolded proteins in the endoplasmic reticulum (ER)
is observed in many human diseases, including cancers. Cellular adaptation to ER stress is …

Cancer statistics in 2018 highlight an 8.6 million incidence in female cancers, and 4.2 million
cancer deaths globally. Moreover, breast cancer is the most frequent malignancy in females …

Cancer is a complex disease involving alterations of multiple processes, with both genetic
and epigenetic features contributing as core factors to the disease. In recent years, it has …

MicroRNAs (miRNAs) are short non-coding RNAs that regulate the function of target genes
at the post-transcriptional phase. miRNAs are considered to have roles in the development …

MicroRNAs (miRNAs) play pivotal roles in numerous biological processes, and their
dysregulation is a common feature of human cancer. Thanks to recent advances in the …

Epigenetic changes are increasingly being appreciated as key events in breast cancer
progression. However, breast cancer subtype-specific epigenetic regulation remains poorly …

Critical features of stem cells include anchoring within a niche and activation upon injury.
Notch signaling maintains skeletal muscle satellite (stem) cell quiescence by inhibiting …