[HTML][HTML] Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations

J Jeevanandam, A Barhoum, YS Chan… - Beilstein journal of …, 2018 - beilstein-journals.org
Nanomaterials (NMs) have gained prominence in technological advancements due to their
tunable physical, chemical and biological properties with enhanced performance over their …

Signal recognition particle: an essential protein-targeting machine

D Akopian, K Shen, X Zhang… - Annual review of …, 2013 - annualreviews.org
The signal recognition particle (SRP) and its receptor compose a universally conserved and
essential cellular machinery that couples the synthesis of nascent proteins to their proper …

[HTML][HTML] Structure of the mammalian ribosome-Sec61 complex to 3.4 Å resolution

RM Voorhees, IS Fernández, SHW Scheres, RS Hegde - Cell, 2014 - cell.com
Cotranslational protein translocation is a universally conserved process for secretory and
membrane protein biosynthesis. Nascent polypeptides emerging from a translating …

Outcome of the first electron microscopy validation task force meeting

R Henderson, A Sali, ML Baker, B Carragher… - Structure, 2012 - cell.com
This Meeting Review describes the proceedings and conclusions from the inaugural
meeting of the Electron Microscopy Validation Task Force organized by the Unified Data …

One number does not fit all: mapping local variations in resolution in cryo-EM reconstructions

G Cardone, JB Heymann, AC Steven - Journal of structural biology, 2013 - Elsevier
The resolution of density maps from single particle analysis is usually measured in terms of
the highest spatial frequency to which consistent information has been obtained. This …

Targeted quantitation of proteins by mass spectrometry

DC Liebler, LJ Zimmerman - Biochemistry, 2013 - ACS Publications
Quantitative measurement of proteins is one of the most fundamental analytical tasks in a
biochemistry laboratory, but widely used immunochemical methods often have limited …

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

TA Rapoport - Nature, 2007 - nature.com
A decisive step in the biosynthesis of many proteins is their partial or complete translocation
across the eukaryotic endoplasmic reticulum membrane or the prokaryotic plasma …

Mechanisms of Sec61/SecY-mediated protein translocation across membranes

E Park, TA Rapoport - Annual review of biophysics, 2012 - annualreviews.org
The Sec61 or SecY channel, a universally conserved protein-conducting channel,
translocates proteins across and integrates proteins into the eukaryotic endoplasmic …

Cryo-EM structure of the ribosome–SecYE complex in the membrane environment

J Frauenfeld, J Gumbart, EO Sluis, S Funes… - Nature structural & …, 2011 - nature.com
Abstract The ubiquitous SecY–Sec61 complex translocates nascent secretory proteins
across cellular membranes and integrates membrane proteins into lipid bilayers. Several …

Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion

M Gogala, T Becker, B Beatrix, JP Armache… - Nature, 2014 - nature.com
The biogenesis of secretory as well as transmembrane proteins requires the activity of the
universally conserved protein-conducting channel (PCC), the Sec61 complex (SecY …