Despite the many advances that have occurred in the field of vaccine adjuvants, there are
still unmet needs that may enable the development of vaccines suitable for more …

Liposomes are widely utilized as a carrier to improve therapeutic efficacy of agents thanks to
their merits of high loading capacity, targeting delivery, reliable protection of agents, good …

Subunit vaccines generally proceed through a 4-step in vivo cascade—the DUMP cascade—
to generate potent cell-mediated immune responses:(1) drainage to lymph nodes;(2) uptake …

In the past decade, gold nanoparticles have attracted strong interest from the
nanobiotechnological community owing to the significant progress made in robust and easy …

A major challenge in vaccine formulations is the stimulation of both the humoral and cellular
immune response for well-defined antigens with high efficacy and safety. Adjuvant research …

Among the emerging subunit vaccines are recombinant protein-and synthetic peptide-based
vaccine formulations. However, proteins and peptides have a low intrinsic immunogenicity …

Among approaches of current cancer immunotherapy, a dendritic cell (DC)-targeted vaccine
based on nanotechnology could be a promising way to efficiently induce potent immune …

Abstract Poly (D, L-lactic-co-glycolic acid)(PLGA)/poly (lactic acid)(PLA) microspheres/
nanoparticles are one of the most successful drug delivery systems (DDS) in lab and clinic …

Tumor nanovaccines have potential applications in the prevention and treatment of
malignant tumors. However, it remains a longstanding challenge in exploiting efficient …

The purpose of the present study was to identify an “easy-to-adopt” strategy to enhance
immune responses using functionalized alginate (ALG) nanoparticles (MAN-ALG/ALG= OVA …