Apelin, an endogenous ligand for the G protein-coupled receptor APJ, is extensively
expressed in various systems, especially the nervous system. This article reviews the role of …

A sedentary lifestyle is associated with overweight/obesity, which involves excessive fat
body accumulation, triggering structural and functional changes in tissues, organs, and body …

Apelin is an endogenous ligand of G protein-coupled receptor APJ. In recent years, many
studies have shown that the apelin/APJ system has neuroprotective properties, such as anti …

Apelin, an endogenous neuropeptide, has been identified as the cognate ligand for the G-
protein-coupled receptor APJ. Apelin, APJ messenger RNA, and protein are widely …

It has been established that cisplatin causes neuronal damage and cognitive impairment.
However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with …

Apelin, a regulatory peptide, is an endogenous ligand of the apelin receptor (APJ), which
belongs to the G protein-coupled receptor family. The peptide and its receptor are distributed …

Although pain has lower mortality rates than cancer, diabetes and stroke, pain is a
predominate source of distress and disability. However, the management of pain remains an …

BACKGROUND: Electroacupuncture (EA) is widely applied for pain management, but the
analgesic effects of EA have not been fully elucidated. In this study, we investigated the …

The incidence of cerebral ischemia has increased in the past decades, and the high fatality
and disability rates seriously affect human health. Apelin is a bioactive peptide and the …

Aim Pulpal pain is a common orofacial health issue that has been linked to cognitive
impairment. Because of its prominent role in pain modulation and cognitive impairment …