Background The soluble cluster of differentiation 14 (or presepsin) is a free fragment of
glycoprotein expressed on monocytes and macrophages. Although many studies have been …

Although the innate immune receptor protein, Receptor for Advanced Glycation End
products (RAGE), has been extensively studied, there has been renewed interest in RAGE …

Background Bloodstream infections remain one of the major challenges in intensive care
units, leading to sepsis or even septic shock in many cases. Due to the lack of timely …

Sepsis is a frequently fatal condition characterized by an uncontrolled and harmful host
reaction to microbial infection. Despite the prevalence and severity of sepsis, we lack a …

Abiotic stresses are the most common harmful factors, adversely affecting all aspects of
plants' life. Plants have to elicit appropriate responses against multifaceted effects of abiotic …

Rationale Sepsis, a global health burden, is often complicated by viral infections leading to
increased long-term morbidity and mortality. Interleukin-3 (IL-3) has been identified as an …

Objectives: The impact of TREM-1-mediated inflammation was investigated in different
inflammatory settings. Methods: Secondary analyses of an observational clinical pilot study …

The immune system plays an essential role in protecting the body against pathogens.
Immune cells are activated during infections, resulting in a metabolic shift from oxidative …

The highly reactive compound methylglyoxal (MG) can cause direct damage to cells and
tissues by reacting with cellular macromolecules. MG has been identified as a biomarker …

Sepsis-related mortality and morbidity are major healthcare problems worldwide 1. Clinical
and laboratory signs of systemic inflammation are neither sensitive nor specific enough for …