Overview on strategies and assays for antibiotic discovery

A Ruetten, T Kirchner, EM Musiol-Kroll - Pharmaceuticals, 2022 - mdpi.com
The increase in antibiotic resistance poses a major threat to global health. Actinomycetes,
the Gram-positive bacteria of the order Actinomycetales, are fertile producers of bioactive …

Importance of microbial amphiphiles: interaction potential of biosurfactants, amyloids, and other exo-polymeric-substances

NG Master, AR Markande - World Journal of Microbiology and …, 2023 - Springer
Microorganisms produce a diverse group of biomolecules having amphipathic nature
(amphiphiles). Microbial amphiphiles, including amyloids, bio-surfactants, and other exo …

Growth Promotion and Disease Suppression Ability of a Streptomyces sp. CB-75 from Banana Rhizosphere Soil

Y Chen, D Zhou, D Qi, Z Gao, J Xie, Y Luo - Frontiers in microbiology, 2018 - frontiersin.org
An actinomycete strain, CB-75, was isolated from the soil of a diseased banana plantation in
Hainan, China. Based on phenotypic and molecular characteristics, and 99.93% sequence …

Taxonomy and Broad-Spectrum Antifungal Activity of Streptomyces sp. SCA3-4 Isolated From Rhizosphere Soil of Opuntia stricta

D Qi, L Zou, D Zhou, Y Chen, Z Gao, R Feng… - Frontiers in …, 2019 - frontiersin.org
Actinobacteria are important producers of bioactive compounds. Extreme ecosystems cause
evolution of novel secondary metabolic pathways of Actinobacteria and increase the …

Antimicrobial biosynthetic potential and diversity of culturable soil actinobacteria from forest ecosystems of Northeast India

P Sharma, D Thakur - Scientific reports, 2020 - nature.com
Actinobacteria is a goldmine for the discovery of abundant secondary metabolites with
diverse biological activities. This study explores antimicrobial biosynthetic potential and …

Antimicrobial potentiality of actinobacteria isolated from two microbiologically unexplored forest ecosystems of Northeast India

R Das, W Romi, R Das, HK Sharma, D Thakur - BMC microbiology, 2018 - Springer
Background Actinobacteria are often known to be great producers of antibiotics. The rapid
increase in the global burden of antibiotic-resistance with the concurrent decline in the …

Antibacterial, anticancer and neuroprotective activities of rare Actinobacteria from mangrove forest soils

AS Azman, I Othman, CM Fang, KG Chan… - Indian journal of …, 2017 - Springer
Mangrove is a complex ecosystem that contains diverse microbial communities, including
rare actinobacteria with great potential to produce bioactive compounds. To date, bioactive …

Newly Isolated Streptomyces sp. JBS5-6 as a Potential Biocontrol Agent to Control Banana Fusarium Wilt: Genome Sequencing and Secondary Metabolite Cluster …

T Jing, D Zhou, M Zhang, T Yun, D Qi, Y Wei… - Frontiers in …, 2020 - frontiersin.org
Banana is a key staple food and fruit in countries all over the world. However, the
development of the global banana industry is seriously threatened by Fusarium wilt disease …

Bioprospection of actinobacteria derived from freshwater sediments for their potential to produce antimicrobial compounds

Zothanpuia, AK Passari, VV Leo, P Chandra… - Microbial cell …, 2018 - Springer
Background Actinobacteria from freshwater habitats have been explored less than from
other habitats in the search for compounds of pharmaceutical value. This study highlighted …

Streptomyces sp. MUM212 as a Source of Antioxidants with Radical Scavenging and Metal Chelating Properties

LTH Tan, KG Chan, TM Khan, SI Bukhari… - Frontiers in …, 2017 - frontiersin.org
Reactive oxygen species and other radicals potentially cause oxidative damage to proteins,
lipids, and DNA which may ultimately lead to various complications including mutations …