Background The detection of mutations in the gyrA and gyrB genes in the Mycobacterium
tuberculosis genome that have been demonstrated to confer phenotypic resistance to …

This monograph is written for healthcare workers in any setting who are faced with the
complex care for patients with tuberculosis. Prevention, diagnosis and treatment of …

Background Diagnosing drug-resistance remains an obstacle to the elimination of
tuberculosis. Phenotypic drug-susceptibility testing is slow and expensive, and commercial …

The emergence of drug-resistant strains of Mycobacterium tuberculosis is a challenge to
global tuberculosis (TB) control. Although culture-based methods have been regarded as …

Background Accurate and rapid tests for tuberculosis (TB) drug resistance are critical for
improving patient care and decreasing the transmission of drug‐resistant TB. Genotype® …

Drug-resistant tuberculosis (TB) poses a significant challenge to the successful treatment
and control of TB worldwide. Resistance to anti-TB drugs has existed since the beginning of …

Background In contrast to drug-sensitive tuberculosis, the guidelines for the treatment of
multi-drug-resistant tuberculosis (MDR-TB) have a very poor evidence base; current …

Background Genotype® MTBDRsl (MTBDRsl) is a rapid DNA‐based test for detecting
specific mutations associated with resistance to fluoroquinolones and second‐line injectable …

Background There is an urgent demand for rapid and accurate drug-susceptibility testing for
the detection of multidrug-resistant tuberculosis. The GenoType MTBDR plus assay is a …

Tuberculosis (TB) is one of the leading causes of adult death in the Asia-Pacific Region,
including Indonesia. As an infectious disease caused by Mycobacterium tuberculosis (MTB) …