The glyoxylate cycle is an anaplerotic pathway of the tricarboxylic acid (TCA) cycle that
allows growth on C2 compounds by bypassing the CO2-generating steps of the TCA cycle …

India already has earned the dubious distinction of being one of the countries with the
highest incidence of tuberculosis (TB). The conventional control measures have had little …

Suppression of major histocompatibility complex (MHC) class II antigen presentation is
believed to be among the major mechanisms used by Mycobacterium tuberculosis to …

Mycobacterium tuberculosis, the causative agent of pulmonary tuberculosis, infects one-third
of the world's population. Activation of host immune responses for containment of …

Mycobacterium tuberculosis complex (MTBC) genomes contain 2 large gene families
termed pe and ppe. The function of pe/ppe proteins remains enigmatic but studies suggest …

Mycobacterium tuberculosis (Mtb) is a remarkably successful pathogen that is capable of
persisting in host tissues for decades without causing disease. Years after initial infection …

Mycobacterium tuberculosis PE/PPE family proteins, named after the presence of conserved
PE (Pro-Glu) and PPE (Pro-Pro-Glu) domains at N-terminal, are prevalent in M. tuberculosis …

We have investigated the role of Rv3097c-encoded lipase (LipY) on the virulence of
Mycobacterium tuberculosis. It has been shown that the overexpression of LipY in strain …

Lysine succinylation (Ksucc) is a newly identified protein posttranslational modification
(PTM), which may play an important role in cellular physiology. However, the role of lysine …

The mycobacterial Rv3097c-encoded lipase LipY is considered as a true lipase involved in
the hydrolysis of triacylglycerol stored in lipid inclusion bodies for the survival of dormant …