The decisive early phase of bone regeneration

GN Duda, S Geissler, S Checa, S Tsitsilonis… - Nature Reviews …, 2023 - nature.com
Bone has a remarkable endogenous regenerative capacity that enables scarless healing
and restoration of its prior mechanical function, even under challenging conditions such as …

Recent advances in extracellular vesicle engineering and its applications to regenerative medicine

WK Rhim, JY Kim, SY Lee, SG Cha, JM Park… - Biomaterials …, 2023 - spj.science.org
Extracellular vesicles (EVs) are nanosized particles that are released from cells and reflect
the characteristics of the mother cell. Recently, the EVs have been used in several types of …

[HTML][HTML] Engineering homologous platelet-rich plasma, platelet-rich plasma-derived exosomes, and mesenchymal stem cell-derived exosomes-based dual …

BM Bakadia, AAQ Ahmed, L Lamboni, Z Shi… - Bioactive Materials, 2023 - Elsevier
The management of diabetic wounds remains a critical therapeutic challenge. Platelet-rich
plasma (PRP) gel, PRP-derived exosomes (PRP-Exos), and mesenchymal stem cell-derived …

[HTML][HTML] Application of 3D-printed hydrogels in wound healing and regenerative medicine

M Deptuła, M Zawrzykraj, J Sawicka… - Biomedicine & …, 2023 - Elsevier
Hydrogels are three-dimensional polymer networks with hydrophilic properties. The
modifiable properties of hydrogels and the structure resembling living tissue allow their …

Bone marrow niches of hematopoietic stem and progenitor cells

O Kandarakov, A Belyavsky, E Semenova - International Journal of …, 2022 - mdpi.com
The mammalian hematopoietic system is remarkably efficient in meeting an organism's vital
needs, yet is highly sensitive and exquisitely regulated. Much of the organismal control over …

Cell culture‐derived extracellular vesicles: Considerations for reporting cell culturing parameters

F Shekari, FJ Alibhai, H Baharvand… - Journal of …, 2023 - Wiley Online Library
Cell culture‐conditioned medium (CCM) is a valuable source of extracellular vesicles (EVs)
for basic scientific, therapeutic and diagnostic applications. Cell culturing parameters affect …

Function and mechanism of mesenchymal stem cells in the healing of diabetic foot wounds

X Yu, P Liu, Z Li, Z Zhang - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetes has become a global public health problem. Diabetic foot is one of the most severe
complications of diabetes, which often places a heavy economic burden on patients and …

Heterogeneity of in vitro expanded mesenchymal stromal cells and strategies to improve their therapeutic actions

L Olmedo-Moreno, Y Aguilera, C Baliña-Sánchez… - Pharmaceutics, 2022 - mdpi.com
Beneficial properties of mesenchymal stromal cells (MSCs) have prompted their use in
preclinical and clinical research. Accumulating evidence has been provided for the …

FIND-seq: high-throughput nucleic acid cytometry for rare single-cell transcriptomics

SW Shin, P Mudvari, S Thaploo, MA Wheeler… - Nature …, 2024 - nature.com
Rare cells have an important role in development and disease, and methods for isolating
and studying cell subsets are therefore an essential part of biology research. Such methods …

Antibacterial and Osteogenic Properties of Ag Nanoparticles and Ag/TiO2 Nanostructures Prepared by Atomic Layer Deposition

D Nazarov, I Ezhov, N Yudintceva, M Shevtsov… - Journal of Functional …, 2022 - mdpi.com
The combination of titania nanofilms and silver nanoparticles (NPs) is a very promising
material, with antibacterial and osseointegration-induced properties for titanium implant …