Meningeal immunity and its function in maintenance of the central nervous system in health and disease
K Alves de Lima, J Rustenhoven… - Annual review of …, 2020 - annualreviews.org
Neuroimmunology, albeit a relatively established discipline, has recently sparked numerous
exciting findings on microglia, the resident macrophages of the central nervous system …
exciting findings on microglia, the resident macrophages of the central nervous system …
[HTML][HTML] The far-reaching scope of neuroinflammation after traumatic brain injury
DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …
of clinical investigations and popular press coverage of athletes and veterans with single or …
[HTML][HTML] Neuroinflammation: microglia and T cells get ready to tango
STT Schetters, D Gomez-Nicola… - Frontiers in …, 2018 - frontiersin.org
In recent years, many paradigms concerning central nervous system (CNS) immunology
have been challenged and shifted, including the discovery of CNS-draining lymphatic …
have been challenged and shifted, including the discovery of CNS-draining lymphatic …
[HTML][HTML] The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases
A DeMaio, S Mehrotra, K Sambamurti… - Journal of …, 2022 - Springer
The adaptive immune system and associated inflammation are vital in surveillance and host
protection against internal and external threats, but can secondarily damage host tissues …
protection against internal and external threats, but can secondarily damage host tissues …
[HTML][HTML] Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer's disease pathology
Alzheimer's disease (AD) is a neurodegenerative disorder in which chronic
neuroinflammation contributes to disease escalation. Nevertheless, while …
neuroinflammation contributes to disease escalation. Nevertheless, while …
Multifaceted interactions between adaptive immunity and the central nervous system
J Kipnis - Science, 2016 - science.org
Neuroimmunologists seek to understand the interactions between the central nervous
system (CNS) and the immune system, both under homeostatic conditions and in diseases …
system (CNS) and the immune system, both under homeostatic conditions and in diseases …
Secondary injury mechanisms in traumatic spinal cord injury: a nugget of this multiply cascade
C Oyinbo - Acta neurobiologiae experimentalis, 2011 - ane.pl
The pathophysiology of acute spinal cord injury (SCI) involves primary and secondary
mechanisms of injury. Though both mechanisms are involved in the neurological …
mechanisms of injury. Though both mechanisms are involved in the neurological …
[HTML][HTML] Inflammation: a target for treatment in spinal cord injury
X Freyermuth-Trujillo, JJ Segura-Uribe… - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) is a significant cause of disability, and treatment alternatives that
generate beneficial outcomes and have no side effects are urgently needed. SCI may be …
generate beneficial outcomes and have no side effects are urgently needed. SCI may be …
[HTML][HTML] Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of …
Recent evidence suggests the commensal microbiome regulates host immunity and
influences brain function; findings that have ramifications for neurodegenerative diseases. In …
influences brain function; findings that have ramifications for neurodegenerative diseases. In …
[PDF][PDF] Dealing with danger in the CNS: the response of the immune system to injury
Fighting pathogens and maintaining tissue homeostasis are prerequisites for survival. Both
of these functions are upheld by the immune system, though the latter is often overlooked in …
of these functions are upheld by the immune system, though the latter is often overlooked in …