Culture media for therapeutic cell preparations—such as mesenchymal stromal cells (MSCs)—
usually comprise serum additives. Traditionally, fetal bovine serum is supplemented in basic …

Stem cell research has been a popular topic in the past few decades. This review aims to
discuss factors that help regulate, induce, and enhance mesenchymal stem cell (MSC) …

In vivo, growth factors exist both as soluble and as solid-phase molecules, immobilized to
cell surfaces and within the extracellular matrix. We used this rationale to develop more …

The use of multipotent human mesenchymal stem cells (hMSCs) for tissue engineering has
been a subject of extensive research. The donor variation in growth, differentiation and in …

Many tissues contain adult mesenchymal stem cells (MSCs), which may be used in tissue
regeneration therapies. However, the MSC availability in most tissues is limited which …

Aging is associated with an increased risk for atherosclerosis. A possible cause is low
numbers and dysfunction of endothelial progenitor cells (EPC) which insufficiently repair …

Prostate cancer is a complex disease in which metastasis to the bone is the main cause of
death. Initial stages of metastasis are generally similar to those for most solid tumors; …

Culture of expanded mesenchymal stem cells (MSCs) seeded on biomaterials may
represent a clinical alternative to autologous bone graft in bone regeneration. Foetal bovine …

Prostate cancer is the second leading cause of cancer‐related death in men. A typical
feature of this disease is its ability to metastasize to bone. It is mainly osteosclerotic, and is …

Bone regeneration is a well organized but complex physiological process, in which different
cell types and their activated signaling pathways are involved. In bone regeneration and …