The vascular endothelium is a monolayer of cells between the vessel lumen and the
vascular smooth muscle cells. Nitric oxide (NO) is a soluble gas continuously synthesized …

Fractional exhaled nitric oxide (FeNO) has gained great clinical importance as a biomarker
of type 2 inflammation in chronic airway diseases such as asthma. FeNO originates primarily …

Radicals are species containing one or more unpaired electrons, such as nitric oxide
(NO•−). The oxygen radical superoxide (O2•−) and the nonradical hydrogen peroxide …

Nitric oxide (NO) produced by the endothelial NO synthase (eNOS) is a fundamental
determinant of cardiovascular homesotasis: it regulates systemic blood pressure, vascular …

Nitric oxide is an inorganic free radical gas, of formula* N= O (abbreviated as NO). The
discovery in 1987/88 that vascular endothelial cells are able to synthesize NO from L …

Peroxynitrite [oxoperoxonitrate (l-), ONOO-] may be formed in vivo from superoxide and nitric
oxide. The anion is stable, but the acid (pK&= 6.8) decays to nitrate with a rate of 1.3 s" 1 at …

The recent discovery of nitric oxide ('NO)'as a mammalian metabolic intermediate has
exploded into a swiftly developing area of research. The intense interest and rapid progress …

S-Nitrosylation is a redox-mediated posttranslational modification that regulates protein
function via covalent reaction of nitric oxide (NO)-related species with a cysteine thiol group …

During the past decade a plethora of studies have unravelled the multiple roles of nitric
oxide (NO) in airway physiology and pathophysiology. In the respiratory tract, NO is …

Penile erection results from a complex interplay between central nervous (cerebral and
spinal) and local factors. Several aspects of these interactions have been the subject of …