The roles of androgens in humans: biology, metabolic regulation and health
M Alemany - International journal of molecular sciences, 2022 - mdpi.com
Androgens are an important and diverse group of steroid hormone molecular species. They
play varied functional roles, such as the control of metabolic energy fate and partition, the …
play varied functional roles, such as the control of metabolic energy fate and partition, the …
Hypogonadism and male obesity: focus on unresolved questions
M Grossmann - Clinical Endocrinology, 2018 - Wiley Online Library
Obesity, increasing in prevalence globally, is the clinical condition most strongly associated
with lowered testosterone concentrations in men and presents as one of the strongest …
with lowered testosterone concentrations in men and presents as one of the strongest …
[HTML][HTML] Effects of long-term testosterone treatment on cardiovascular outcomes in men with hypogonadism: rationale and design of the TRAVERSE study
S Bhasin, AM Lincoff, S Basaria, DC Bauer… - American Heart …, 2022 - Elsevier
Background Testosterone exerts some effects on the cardiovascular system that could be
considered beneficial; some other effects may potentially increase the risk of cardiovascular …
considered beneficial; some other effects may potentially increase the risk of cardiovascular …
Aging and the male reproductive system
This narrative review presents an overview of current knowledge on fertility and reproductive
hormone changes in aging men, the factors driving and modulating these changes, their …
hormone changes in aging men, the factors driving and modulating these changes, their …
Obesity and male hypogonadism: Tales of a vicious cycle
Obesity prevalence, particularly in children and young adults, is perilously increasing
worldwide foreseeing serious negative health impacts in the future to come. Obesity is linked …
worldwide foreseeing serious negative health impacts in the future to come. Obesity is linked …
Mechanisms underlying the metabolic actions of testosterone in humans: a narrative review
The role of testosterone in improving sexual symptoms in men with hypogonadism is well
known. However, recent studies indicate that testosterone plays an important role in several …
known. However, recent studies indicate that testosterone plays an important role in several …
Late‐onset hypogonadism: metabolic impact
M Grossmann, M Ng Tang Fui, AS Cheung - Andrology, 2020 - Wiley Online Library
Background Obesity and dysglycemia (comprising insulin resistance, the metabolic
syndrome and type 2 diabetes), that is diabesity, are associated with reduced circulating …
syndrome and type 2 diabetes), that is diabesity, are associated with reduced circulating …
Metabolic changes in patients with prostate cancer during androgen deprivation therapy
K Mitsuzuka, Y Arai - International Journal of Urology, 2018 - Wiley Online Library
Androgen deprivation therapy continues to be widely used for the treatment of prostate
cancer despite the appearance of new‐generation androgen‐receptor targeting drugs after …
cancer despite the appearance of new‐generation androgen‐receptor targeting drugs after …
Metabolic syndrome and male fertility: beyond heart consequences of a complex cardiometabolic endocrinopathy
G Salvio, A Ciarloni, M Cutini, N Delli Muti… - International Journal of …, 2022 - mdpi.com
Metabolic syndrome (MetS) is a highly prevalent condition among adult males, affecting up
to 41% of men in Europe. It is characterized by the association of obesity, hypertension, and …
to 41% of men in Europe. It is characterized by the association of obesity, hypertension, and …
[HTML][HTML] Obesity, body composition, and sex hormones: implications for cardiovascular risk
Cardiovascular disease (CVD) continues to be the leading cause of death in adults,
highlighting the need to develop novel strategies to mitigate cardiovascular risk. The …
highlighting the need to develop novel strategies to mitigate cardiovascular risk. The …