Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

The clinical effect of sperm DNA damage in assisted reproduction has been a controversial
topic during recent decades, leading to a variety of clinical practice recommendations. While …

The study aims to discuss the effects of aging on the male reproductive system. A systematic
review was performed using PubMed from 1980 to 2014. Aging is a natural process …

STUDY QUESTION Does microfluidic sorting improve the selection of sperm with lower DNA
fragmentation over standard density-gradient centrifugation? SUMMARY ANSWER …

Reproductive diseases have become a growing worldwide problem and male factor plays
an important role in the reproductive diagnosis, prognosis and design of assisted …

Assessments of sperm DNA damage are controversial because of perceived uncertainties
over the relationship with pregnancy and the limited range of therapies available should …

Objective To analyze the effect of single-and double-stranded sperm DNA fragmentation
(ssSDF and dsSDF) on human embryo kinetics monitored under a time-lapse system …

Background Physical activity (PA) and sedentary behavior have inconsistent effects on
fertility. High body mass index is associated with infertility but to our knowledge, very few …

Abnormal standard semen characteristics and reduced sperm chromatin maturity can
appear with increasing male age. However, the influence of paternal age on semen …

This study assessed sperm quality declining on relation to paternal age and its impact on in
vitro fertilization (IVF) outcomes in order to estimate the APA (Advanced Paternal Age) cutoff …