Recent advances in viral metagenomics have enabled the rapid discovery of an
unprecedented catalogue of phages in numerous environments, from the human gut to the …

Viruses and other selfish genetic elements are dominant entities in the biosphere, with
respect to both physical abundance and genetic diversity. Various selfish elements …

Ocean microbes drive biogeochemical cycling on a global scale. However, this cycling is
constrained by viruses that affect community composition, metabolic activity, and …

Motivation Bacterial and archaeal viruses are crucial for global biogeochemical cycles and
might well be game-changing therapeutic agents in the fight against multi-resistant …

Bacteriophages from the Inoviridae family (inoviruses) are characterized by their unique
morphology, genome content and infection cycle. One of the most striking features of …

Bacteriophages, which are viruses infecting bacteria, are the most ubiquitous and diverse
entities in the biosphere. There is accumulating evidence revealing their important roles in …

Viruses are the most abundant biological entities on earth and show remarkable diversity of
genome sequences, replication and expression strategies, and virion structures …

The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Tailed bacteriophages with genomes larger than 200 kbp are classified as Jumbo phages,
and are rarely isolated by conventional methods. These phages are designated “jumbo” …

The bacterial and archaeal CRISPR/Cas adaptive immune system targets specific
protospacer nucleotide sequences in invading organisms. This requires base pairing …