Aneurysmal subarachnoid hemorrhage: the last decade

SN Neifert, EK Chapman, ML Martini… - Translational stroke …, 2021 - Springer
Aneurysmal subarachnoid hemorrhage (SAH) affects six to nine people per 100,000 per
year, has a 35% mortality, and leaves many with lasting disabilities, often related to cognitive …

Delayed neurological deterioration after subarachnoid haemorrhage

RL Macdonald - Nature Reviews Neurology, 2014 - nature.com
Subarachnoid haemorrhage (SAH) causes early brain injury (EBI) that is mediated by effects
of transient cerebral ischaemia during bleeding plus effects of the subarachnoid blood …

Delayed cerebral ischemia after subarachnoid hemorrhage: beyond vasospasm and towards a multifactorial pathophysiology

JR Geraghty, FD Testai - Current atherosclerosis reports, 2017 - Springer
Abstract Purpose of Review Delayed cerebral ischemia (DCI) is common after subarachnoid
hemorrhage (SAH) and represents a significant cause of poor functional outcome. DCI was …

The pathophysiology and treatment of delayed cerebral ischaemia following subarachnoid haemorrhage

KP Budohoski, M Guilfoyle, A Helmy… - Journal of Neurology …, 2014 - jnnp.bmj.com
Cerebral vasospasm has traditionally been regarded as an important cause of delayed
cerebral ischaemia (DCI) which occurs after aneurysmal subarachnoid haemorrhage, and …

Neuroinflammation as a target for intervention in subarachnoid hemorrhage

AL de Oliveira Manoel, RL Macdonald - Frontiers in neurology, 2018 - frontiersin.org
Aneurysmal subarachnoid hemorrhage (SAH) is a sub-type of hemorrhagic stroke
associated with the highest rates of mortality and long-term neurological disabilities. Despite …

Hydrogen-rich saline attenuated subarachnoid hemorrhage-induced early brain injury in rats by suppressing inflammatory response: possible involvement of NF-κB …

A Shao, H Wu, Y Hong, S Tu, X Sun, Q Wu… - Molecular …, 2016 - Springer
Early brain injury (EBI), highlighted with inflammation and apoptosis, occurring within 72 h
after subarachnoid hemorrhage (SAH), is associated with the prognosis of SAH. Recent …

Neuroinflammation and microvascular dysfunction after experimental subarachnoid hemorrhage: emerging components of early brain injury related to outcome

JR Geraghty, JL Davis, FD Testai - Neurocritical care, 2019 - Springer
Aneurysmal subarachnoid hemorrhage has a high mortality rate and, for those who survive
this devastating injury, can lead to lifelong impairment. Clinical trials have demonstrated that …

An introduction to the pathophysiology of aneurysmal subarachnoid hemorrhage

JH van Lieshout, M Dibué-Adjei, JF Cornelius… - Neurosurgical …, 2018 - Springer
Pathophysiological processes following subarachnoid hemorrhage (SAH) present survivors
of the initial bleeding with a high risk of morbidity and mortality during the course of the …

The role of the microcirculation in delayed cerebral ischemia and chronic degenerative changes after subarachnoid hemorrhage

L Østergaard, R Aamand… - Journal of Cerebral …, 2013 - journals.sagepub.com
The mortality after aneurysmal subarachnoid hemorrhage (SAH) is 50%, and most survivors
suffer severe functional and cognitive deficits. Half of SAH patients deteriorate 5 to 14 days …

The pathophysiology of delayed cerebral ischemia

B Foreman - Journal of Clinical Neurophysiology, 2016 - journals.lww.com
Subarachnoid hemorrhage (SAH) affects 30,000 people in the Unites States alone each
year. Delayed cerebral ischemia occurs days after subarachnoid hemorrhage and …