Alzheimer's retinopathy: seeing disease in the eyes

N Mirzaei, H Shi, M Oviatt, J Doustar… - Frontiers in …, 2020 - frontiersin.org
The neurosensory retina emerges as a prominent site of Alzheimer's disease (AD)
pathology. As a CNS extension of the brain, the neuro retina is easily accessible for …

Visual and ocular manifestations of Alzheimer's disease and their use as biomarkers for diagnosis and progression

FZ Javaid, J Brenton, L Guo, MF Cordeiro - Frontiers in neurology, 2016 - frontiersin.org
Alzheimer's disease (AD) is the most common form of dementia affecting the growing aging
population today, with prevalence expected to rise over the next 35 years. Clinically, patients …

Optical coherence tomography in Alzheimer's disease: a meta-analysis

G Coppola, A Di Renzo, L Ziccardi, F Martelli, A Fadda… - PloS one, 2015 - journals.plos.org
Background Alzheimer's disease (AD) is a neurodegenerative disorder, which is likely to
start as mild cognitive impairment (MCI) several years before the its full-blown clinical …

Changes in visual function and retinal structure in the progression of Alzheimer's disease

E Salobrar-García, R de Hoz, AI Ramírez… - PloS one, 2019 - journals.plos.org
Background Alzheimer's Disease (AD) can cause degeneration in the retina and optic nerve
either directly, as a result of amyloid beta deposits, or secondarily, as a result of the …

Sensory processing deficits and related cortical pathological changes in Alzheimer's disease

NK Zhang, SK Zhang, LI Zhang, HW Tao… - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily affecting
cognitive functions. However, sensory deficits in AD start to draw attention due to their high …

The retina as a window or mirror of the brain changes detected in Alzheimer's disease: critical aspects to unravel

S Chiquita, AC Rodrigues-Neves, FI Baptista… - Molecular …, 2019 - Springer
Alzheimer's disease is the most frequent cause of dementia worldwide, representing a
global health challenge, with a massive impact on the quality of life of Alzheimer's disease …

[HTML][HTML] The retina in Alzheimer's disease: histomorphometric analysis of an ophthalmologic biomarker

S Asanad, FN Ross-Cisneros, M Nassisi… - … & Visual Science, 2019 - tvst.arvojournals.org
Methods: Human postmortem retinas from eight patients with AD (mean age: 80±12.7 years)
and from 11 age-matched controls (mean age: 78±16.57 years) were analyzed. The retinas …

Vision function abnormalities in Alzheimer disease

R Tzekov, M Mullan - Survey of Ophthalmology, 2014 - Elsevier
Alzheimer disease (AD) is a progressive, age-related debilitating condition that is a growing
public health problem in the developed world. Visual system abnormalities in AD were …

Visual impairment in Alzheimer's disease: a critical review

E Kirby, S Bandelow… - Journal of Alzheimer's …, 2010 - content.iospress.com
Visual impairment is a common symptom of Alzheimer's disease (AD). Recent studies have
demonstrated the potential of visual interventions to improve the functioning of AD patients …

Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline

S Asanad, M Fantini, W Sultan, M Nassisi, CM Felix… - PLoS …, 2020 - journals.plos.org
Background Alzheimer's disease (AD) pathology precedes symptoms and its detection can
identify at-risk individuals who may benefit from early treatment. Since the retinal nerve fiber …