Epithelial–mesenchymal transition (EMT) and endothelial–mesenchymal transition (EndMT)
are physiological processes required for normal embryogenesis. However, these processes …

The TGF-β signaling pathway plays a crucial role in several key aspects of development and
tissue homeostasis. TGF-β ligands and their mediators have been shown to be important …

Purpose: To investigate the course of inflammatory and angiogenic cytokines in the aqueous
humor of patients with persistent/recurrent neovascular age-related macular degeneration …

The multifunctional transforming growth factors-beta (TGF-βs) have been extensively studied
regarding their role in the pathogenesis of neovascular age-related macular degeneration …

Choroidal neovascularization (CNV) is the most severe complication in Age-related macular
degeneration (AMD) and the most common cause of irreversible blindness in the elderly in …

Purpose: The purpose of this study was to evaluate the expression of high-temperature
requirement A serine peptidase 1 (HTRA1), TGF-β1, bone morphogenetic protein 4 (BMP4) …

Purpose: To determine, using an aptamer-based technology in patients with intermediate
age-related macular degeneration (AMD),(1) if there is a difference in plasma levels of 4979 …

Neovascular AMD (nAMD) leads to vision loss and is a leading cause of visual impairment
in the industrialised world. Current treatments that target blood vessel growth have not been …

Objective Choroidal neovascularization (CNV) is a major cause of vision loss in retinal
diseases such as age-related macular degeneration (AMD). Previously, we demonstrated …

Age-related macular degeneration (AMD) is one of the major causes of irreversible
blindness among aging populations in developed countries and can be classified as dry or …