An overview of STRUCTURE: applications, parameter settings, and supporting software

L Porras-Hurtado, Y Ruiz, C Santos, C Phillips… - Frontiers in …, 2013 - frontiersin.org
Objectives: We present an up-to-date review of STRUCTURE software: one of the most
widely used population analysis tools that allows researchers to assess patterns of genetic …

Linkage disequilibrium in humans: models and data

JK Pritchard, M Przeworski - The American Journal of Human Genetics, 2001 - cell.com
In this review, we describe recent empirical and theoretical work on the extent of linkage
disequilibrium (LD) in the human genome, comparing the predictions of simple population …

Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies

D Falush, M Stephens, JK Pritchard - Genetics, 2003 - academic.oup.com
We describe extensions to the method of Pritchard et al. for inferring population structure
from multilocus genotype data. Most importantly, we develop methods that allow for linkage …

Interpreting population-and family-based genome-wide association studies in the presence of confounding

C Veller, GM Coop - PLoS Biology, 2024 - journals.plos.org
A central aim of genome-wide association studies (GWASs) is to estimate direct genetic
effects: the causal effects on an individual's phenotype of the alleles that they carry …

Patterns of linkage disequilibrium in the human genome

KG Ardlie, L Kruglyak, M Seielstad - Nature Reviews Genetics, 2002 - nature.com
Particular alleles at neighbouring loci tend to be co-inherited. For tightly linked loci, this
might lead to associations between alleles in the population—a property known as linkage …

[图书][B] Human evolutionary genetics: origins, peoples and disease

M Jobling, C Tyler-Smith - 2019 - taylorfrancis.com
Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …

Genomic selection models double the accuracy of predicted breeding values for bacterial cold water disease resistance compared to a traditional pedigree-based …

RL Vallejo, TD Leeds, G Gao, JE Parsons… - Genetics Selection …, 2017 - Springer
Background Previously, we have shown that bacterial cold water disease (BCWD)
resistance in rainbow trout can be improved using traditional family-based selection, but …

[HTML][HTML] Modeling 3D facial shape from DNA

P Claes, DK Liberton, K Daniels, KM Rosana… - PLoS …, 2014 - journals.plos.org
Human facial diversity is substantial, complex, and largely scientifically unexplained. We
used spatially dense quasi-landmarks to measure face shape in population samples with …

Common genetic variation and breast cancer risk—past, present, and future

J Lilyquist, KJ Ruddy, CM Vachon, FJ Couch - … Epidemiology, Biomarkers & …, 2018 - AACR
Breast cancer is the most common cancer among women in the United States, with up to
30% of those diagnosed displaying a family history of breast cancer. To date, 18% of the …

Skin pigmentation, biogeographical ancestry and admixture mapping

MD Shriver, EJ Parra, S Dios, C Bonilla, H Norton… - Human genetics, 2003 - Springer
Ancestry informative markers (AIMs) are genetic loci showing alleles with large frequency
differences between populations. AIMs can be used to estimate biogeographical ancestry at …