An overview of STRUCTURE: applications, parameter settings, and supporting software
L Porras-Hurtado, Y Ruiz, C Santos, C Phillips… - Frontiers in …, 2013 - frontiersin.org
Objectives: We present an up-to-date review of STRUCTURE software: one of the most
widely used population analysis tools that allows researchers to assess patterns of genetic …
widely used population analysis tools that allows researchers to assess patterns of genetic …
Linkage disequilibrium in humans: models and data
JK Pritchard, M Przeworski - The American Journal of Human Genetics, 2001 - cell.com
In this review, we describe recent empirical and theoretical work on the extent of linkage
disequilibrium (LD) in the human genome, comparing the predictions of simple population …
disequilibrium (LD) in the human genome, comparing the predictions of simple population …
Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies
We describe extensions to the method of Pritchard et al. for inferring population structure
from multilocus genotype data. Most importantly, we develop methods that allow for linkage …
from multilocus genotype data. Most importantly, we develop methods that allow for linkage …
Interpreting population-and family-based genome-wide association studies in the presence of confounding
A central aim of genome-wide association studies (GWASs) is to estimate direct genetic
effects: the causal effects on an individual's phenotype of the alleles that they carry …
effects: the causal effects on an individual's phenotype of the alleles that they carry …
Patterns of linkage disequilibrium in the human genome
KG Ardlie, L Kruglyak, M Seielstad - Nature Reviews Genetics, 2002 - nature.com
Particular alleles at neighbouring loci tend to be co-inherited. For tightly linked loci, this
might lead to associations between alleles in the population—a property known as linkage …
might lead to associations between alleles in the population—a property known as linkage …
[图书][B] Human evolutionary genetics: origins, peoples and disease
M Jobling, C Tyler-Smith - 2019 - taylorfrancis.com
Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …
together molecular genetics and genomics to the study of the origins and movements of …
Genomic selection models double the accuracy of predicted breeding values for bacterial cold water disease resistance compared to a traditional pedigree-based …
RL Vallejo, TD Leeds, G Gao, JE Parsons… - Genetics Selection …, 2017 - Springer
Background Previously, we have shown that bacterial cold water disease (BCWD)
resistance in rainbow trout can be improved using traditional family-based selection, but …
resistance in rainbow trout can be improved using traditional family-based selection, but …
[HTML][HTML] Modeling 3D facial shape from DNA
P Claes, DK Liberton, K Daniels, KM Rosana… - PLoS …, 2014 - journals.plos.org
Human facial diversity is substantial, complex, and largely scientifically unexplained. We
used spatially dense quasi-landmarks to measure face shape in population samples with …
used spatially dense quasi-landmarks to measure face shape in population samples with …
Common genetic variation and breast cancer risk—past, present, and future
J Lilyquist, KJ Ruddy, CM Vachon, FJ Couch - … Epidemiology, Biomarkers & …, 2018 - AACR
Breast cancer is the most common cancer among women in the United States, with up to
30% of those diagnosed displaying a family history of breast cancer. To date, 18% of the …
30% of those diagnosed displaying a family history of breast cancer. To date, 18% of the …
Skin pigmentation, biogeographical ancestry and admixture mapping
Ancestry informative markers (AIMs) are genetic loci showing alleles with large frequency
differences between populations. AIMs can be used to estimate biogeographical ancestry at …
differences between populations. AIMs can be used to estimate biogeographical ancestry at …