NANETS/SNMMI consensus statement on patient selection and appropriate use of 177Lu-DOTATATE peptide receptor radionuclide therapy

TA Hope, L Bodei, JA Chan, G El-Haddad… - Journal of Nuclear …, 2020 - Soc Nuclear Med
MATERIALS AND METHODS Systematic Review To inform the development of these
guidelines, a systematic review of evidence was performed. We followed the Preferred …

Therapeutic strategies for neuroendocrine liver metastases

A Frilling, AK Clift - Cancer, 2015 - Wiley Online Library
Patients who have neuroendocrine tumors frequently present with liver metastases. A wide
panel of treatment options exists for these patients. Liver resection with curative intent …

177Lu-Dotatate plus long-acting octreotide versus high‑dose long-acting octreotide in patients with midgut neuroendocrine tumours (NETTER-1): final overall survival …

JR Strosberg, ME Caplin, PL Kunz… - The Lancet …, 2021 - thelancet.com
Background The primary analysis of the phase 3 NETTER-1 trial showed significant
improvement in progression-free survival with 177 Lu-Dotatate plus long-acting octreotide …

[HTML][HTML] Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors

J Strosberg, G El-Haddad, E Wolin… - … England Journal of …, 2017 - Mass Medical Soc
Background Patients with advanced midgut neuroendocrine tumors who have had disease
progression during first-line somatostatin analogue therapy have limited therapeutic options …

Efficacy and safety of high-specific-activity 131I-MIBG therapy in patients with advanced pheochromocytoma or paraganglioma

DA Pryma, BB Chin, RB Noto, JS Dillon… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Patients with metastatic or unresectable (advanced) pheochromocytoma and
paraganglioma (PPGL) have poor prognoses and few treatment options. This multicenter …

The North American neuroendocrine tumor society consensus guidelines for surveillance and medical management of pancreatic neuroendocrine tumors

TR Halfdanarson, JR Strosberg, L Tang, AM Bellizzi… - Pancreas, 2020 - journals.lww.com
This article is the result of the North American Neuroendocrine Tumor Society consensus
conference on the medical management of pancreatic neuroendocrine tumors from July 19 …

213Bi-DOTATOC receptor-targeted alpha-radionuclide therapy induces remission in neuroendocrine tumours refractory to beta radiation: a first-in-human experience

C Kratochwil, FL Giesel, F Bruchertseifer… - European journal of …, 2014 - Springer
Purpose Radiopeptide therapy using a somatostatin analogue labelled with a beta emitter
such as 90 Y/177 Lu-DOTATOC is a new therapeutic option in neuroendocrine cancer …

Dose mapping after endoradiotherapy with 177Lu-DOTATATE/DOTATOC by a single measurement after 4 days

H Hänscheid, C Lapa, AK Buck… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Dosimetry of organs and tumors helps to assess risks and benefit of treatment with 177Lu-
DOTATATE/DOTATOC. However, it is often not performed in clinical routine because of …

[HTML][HTML] Results and adverse events of personalized peptide receptor radionuclide therapy with 90Yttrium and 177Lutetium in 1048 patients with neuroendocrine …

RP Baum, HR Kulkarni, A Singh, D Kaemmerer… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Methods In our center, 2294 patients were screened between 2004 and 2014 by 68 Ga
somatostatin receptor (SSTR) PET/CT. Intention to treat analysis included 1048 patients …

Subacute haematotoxicity after PRRT with 177Lu-DOTA-octreotate: prognostic factors, incidence and course

H Bergsma, MW Konijnenberg, BLR Kam… - European journal of …, 2016 - Springer
Purpose In peptide receptor radionuclide therapy (PRRT), the bone marrow (BM) is one of
the dose-limiting organs. The accepted dose limit for BM is 2 Gy, adopted from 131 I …