Amino acids are the building blocks of protein synthesis. They are structural elements and
energy sources of cells necessary for normal cell growth, differentiation and function. Amino …

Metabolism rewiring is an important hallmark of cancers. Being one of the most abundant
free amino acids in the human blood, glutamine supports bioenergetics and biosynthesis …

Recent discoveries in cancer metabolism have revealed promising metabolic targets to
modulate cancer progression, drug response, and anti-cancer immunity. Combination …

Colorectal carcinoma (CRC) is one of the most frequently diagnosed carcinomas and one of
the leading causes of cancer-related death worldwide. Metabolic reprogramming, a hallmark …

Neutrophil extracellular traps (NETs), a web-like structure of cytosolic and granule proteins
assembled on decondensed chromatin, kill pathogens and cause tissue damage in …

Background Trastuzumab is a first‐line targeted therapy for human epidermal growth factor
receptor‐2 (HER2)‐positive gastric cancer. However, the inevitable occurrence of acquired …

Background Synovial fibroblasts in rheumatoid arthritis (RAFLS) exhibit a pathological
aberration of glycolysis and glutaminolysis. Henceforth, we aimed to investigate if dual …

With high prevalence and mortality, together with metabolic reprogramming, colorectal
cancer is a leading cause of cancer-related death. Metabolic reprogramming gives tumors …

Distant metastasis remains a leading cause of mortality among patients with colorectal
cancer (CRC). Organotropism, referring to the propensity of metastasis to target specific …

Colorectal cancer (CRC) is one of the most frequently diagnosed cancers worldwide.
Metabolic reprogramming represents an important cancer hallmark in CRC. Reprogramming …