Molecular insight into invasive group A streptococcal disease

JN Cole, TC Barnett, V Nizet, MJ Walker - Nature Reviews Microbiology, 2011 - nature.com
Streptococcus pyogenes is also known as group A Streptococcus (GAS) and is an important
human pathogen that causes considerable morbidity and mortality worldwide. The GAS …

Distribution and physiology of ABC-type transporters contributing to multidrug resistance in bacteria

J Lubelski, WN Konings… - … and molecular biology …, 2007 - Am Soc Microbiol
Membrane proteins responsible for the active efflux of structurally and functionally unrelated
drugs were first characterized in higher eukaryotes. To date, a vast number of transporters …

Limonene inhibits streptococcal biofilm formation by targeting surface-associated virulence factors

GA Subramenium, K Vijayakumar… - Journal of medical …, 2015 - microbiologyresearch.org
The present study explores the efficacy of limonene, a cyclic terpene found in the rind of
citrus fruits, for antibiofilm potential against species of the genus Streptococcus, which have …

Zinc disrupts central carbon metabolism and capsule biosynthesis in Streptococcus pyogenes

CLY Ong, MJ Walker, AG McEwan - Scientific reports, 2015 - nature.com
Neutrophils release free zinc to eliminate the phagocytosed bacterial pathogen
Streptococcus pyogenes (Group A Streptococcus; GAS). In this study, we investigated the …

Induction of group A Streptococcus virulence by a human antimicrobial peptide

I Gryllos, HJ Tran-Winkler, MF Cheng… - Proceedings of the …, 2008 - National Acad Sciences
Group A streptococci (Streptococcus pyogenes or GAS) freshly isolated from individuals with
streptococcal sore throat or invasive (“flesh-eating”) infection often grow as mucoid colonies …

The role of complex carbohydrate catabolism in the pathogenesis of invasive streptococci

SA Shelburne, MT Davenport, DB Keith… - Trends in microbiology, 2008 - cell.com
Historically, the study of bacterial catabolism of complex carbohydrates has contributed to
understanding basic bacterial physiology. Recently, however, genome-wide screens of …

The two faces of Janus: virulence gene regulation by CovR/S in group A streptococci

G Churchward - Molecular microbiology, 2007 - Wiley Online Library
The group A streptococcus (GAS) causes a variety of human diseases, including toxic shock
syndrome and necrotizing fasciitis, which are both associated with significant mortality. Even …

A decade of molecular pathogenomic analysis of group A Streptococcus

JM Musser, SA Shelburne - The Journal of clinical …, 2009 - Am Soc Clin Investig
Molecular pathogenomic analysis of the human bacterial pathogen group A Streptococcus
has been conducted for a decade. Much has been learned as a consequence of the …

The potentiality of Wickerhamomyces anomalus against postharvest black spot disease in cherry tomatoes and insights into the defense mechanisms involved

FA Raynaldo, M Ackah, GLN Ngea, SA Rehman… - Postharvest Biology and …, 2024 - Elsevier
Our previous study revealed that Wickerhamomyces anomalus effectively inhibited Botrytis
cinerea disease in cherry tomatoes. However, the potentiality of W. anomalus against black …

[HTML][HTML] Virulence-related transcriptional regulators of Streptococcus pyogenes

LA Vega, H Malke, KS McIver - Streptococcus pyogenes: Basic …, 2022 - ncbi.nlm.nih.gov
Control of virulence gene expression in S. pyogenes is under the charge of 13 two-
component regulatory systems and at least 30 transcriptional regulators known thus far …