Glioblastoma multiforme (GBM), an aggressive tumor that typically exhibits treatment failure
with high mortality rates, is associated with the presence of cancer stem cells (CSCs) within …

Simple Summary Glioblastoma is one of the most treatment-refractory human malignancies,
and despite techniques that have allowed scientists and clinicians to better understand the …

JAK-STAT is an efficient and highly regulated system mainly dedicated to the regulation of
gene expression. Primarily identified as functioning in hematopoietic cells, its role has been …

Glioblastoma (GBM) is the most common malignant adult brain cancer with no curative
treatment strategy. A significant hurdle in GBM treatment is effective therapeutic delivery to …

Despite considerable amount of research, the poor prognosis of patients diagnosed with
glioblastoma multiforme (GBM) critically needs new drug development to improve clinical …

Evidence has suggested that STAT3 functions as an oncogene in gliomagenesis. As a
consequence, changes in the inflammatory microenvironment are thought to promote tumor …

Glioblastoma is a highly aggressive brain tumor that is characterized by its unparalleled
invasiveness. Invasive glioblastoma cells not only escape surgery and focal therapies but …

Background Although the satellite cell (SC) is a key regulator of muscle growth during
development and muscle adaptation following exercise, the regulation of human muscle SC …

Glioblastoma is the most common type of malignant brain tumor among adults and is
currently a non‑curable disease due primarily to its highly invasive phenotype, and the lack …

Glioblastoma (GBM) continues to be the most aggressive cancer of the brain. The dismal
prognosis is largely attributed to the microenvironment surrounding tumor cells. Astrocytes …