Obesity and its related health complications is a major problem worldwide. Hypothalamus
and their signalling molecules play a critical role in the intervening and coordination with …

This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

As we enter the 21st century, a new era of nutrition in the prevention and treatment of
disease emerges. Clinical nutrition involves the integration of diet, genetics, environment …

Obesity is an important cause of morbidity and mortality in developed countries, and is also
becoming increasingly prevalent in the developing world. Although environmental factors …

The role of genetics in obesity is twofold. Studying rare mutations in humans and model
organisms provides fundamental insight into a complex physiological process, and …

Despite recent advances in the molecular genetics of type 2 diabetes, the majority of
susceptibility genes in humans remain to be identified. We therefore conducted a 10-cM …

Recent research has emphasized the importance of the metabolic cluster, which includes
glucose intolerance, dyslipidemia, and high blood pressure, as a strong predictor of the …

Obesity has become a global epidemic and contributes to the increasing burden of type 2
diabetes, cardiovascular disease, stroke, some types of cancer, and premature death …

Loos RJF, Bouchard C (Human Genomics Laboratory, Pennington Biomedical Research
Center, Baton Rouge, LA, USA). Obesity–is it a genetic disorder?(Review). J Intern Med …

Many" complex" human diseases, which involve multiple genetic and environmental
determinants, have increased in incidence during the past 2 decades. During the same time …