Regeneration is one of the great mysteries of biology. Planarians are flatworms capable of
dramatic feats of regeneration, which have been studied for over 2 centuries. Recent …

The capacity for regeneration is broad in the animal kingdom. Planarians are flatworms that
can regenerate any missing body part and their regenerative powers have combined with …

Planarian whole-body regeneration is enabled by stem cells called neoblasts. At least some
neoblasts are individually pluripotent. Neoblasts are also heterogeneous, with …

Proper function and repair of the digestive system are vital to most animals. Deciphering the
mechanisms involved in these processes requires an atlas of gene expression and cell …

Planarians are flatworms capable of regenerating any missing body part in a process
requiring stem cells and positional information. Muscle is a major source of planarian …

Planarians are flatworms capable of whole-body regeneration, able to regrow any missing
body part after injury or amputation. The extraordinary regenerative capacity of planarians is …

Abstract Background In the Lophotrochozoa/Spiralia superphylum, few organisms have as
high a capacity for rapid testing of gene function and single-cell transcriptomics as the …

Transcription factors are pivotal regulators of gene transcription, and many diseases are
associated with the deregulation of transcriptional networks. In the heart, the transcription …

The extracellular matrix (ECM) provides a precise physical and molecular environment for
cell maintenance, self-renewal, and differentiation in the stem cell niche. However, the …

Increasing microplastics pollution of marine and terrestrial water is a concerning issue for
ecosystems and human health. Nevertheless, the interaction of microplastics with freshwater …