[HTML][HTML] Fluorescence imaging of large-scale neural ensemble dynamics

TH Kim, MJ Schnitzer - Cell, 2022 - cell.com
Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …

Integration of optogenetics with complementary methodologies in systems neuroscience

CK Kim, A Adhikari, K Deisseroth - Nature Reviews Neuroscience, 2017 - nature.com
Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …

[HTML][HTML] CaImAn an open source tool for scalable calcium imaging data analysis

A Giovannucci, J Friedrich, P Gunn, J Kalfon, BL Brown… - elife, 2019 - elifesciences.org
Advances in fluorescence microscopy enable monitoring larger brain areas in-vivo with finer
time resolution. The resulting data rates require reproducible analysis pipelines that are …

Next-generation probes, particles, and proteins for neural interfacing

J Rivnay, H Wang, L Fenno, K Deisseroth… - Science …, 2017 - science.org
Bidirectional interfacing with the nervous system enables neuroscience research, diagnosis,
and therapy. This two-way communication allows us to monitor the state of the brain and its …

[HTML][HTML] Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data

P Zhou, SL Resendez, J Rodriguez-Romaguera… - elife, 2018 - elifesciences.org
In vivo calcium imaging through microendoscopic lenses enables imaging of previously
inaccessible neuronal populations deep within the brains of freely moving animals …

In vivo imaging of neural activity

W Yang, R Yuste - Nature methods, 2017 - nature.com
Since the introduction of calcium imaging to monitor neuronal activity with single-cell
resolution, optical imaging methods have revolutionized neuroscience by enabling …

[HTML][HTML] Thermally drawn advanced functional fibers: New frontier of flexible electronics

W Yan, C Dong, Y Xiang, S Jiang, A Leber, G Loke… - Materials Today, 2020 - Elsevier
Electronic devices are evolving from rigid devices into flexible and stretchable structures,
enabling a seamless integration of electronics into our everyday lives. The integration of a …

Whole-brain functional imaging at cellular resolution using light-sheet microscopy

MB Ahrens, MB Orger, DN Robson, JM Li, PJ Keller - Nature methods, 2013 - nature.com
Brain function relies on communication between large populations of neurons across
multiple brain areas, a full understanding of which would require knowledge of the time …

Next-generation interfaces for studying neural function

JA Frank, MJ Antonini, P Anikeeva - Nature biotechnology, 2019 - nature.com
Monitoring and modulating the diversity of signals used by neurons and glia in a closed-loop
fashion is necessary to establish causative links between biochemical processes within the …

Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain

CK Kim, SJ Yang, N Pichamoorthy, NP Young… - Nature …, 2016 - nature.com
Real-time activity measurements from multiple specific cell populations and projections are
likely to be important for understanding the brain as a dynamical system. Here we …