Ammon's horn sclerosis: a maldevelopmental disorder associated with temporal lobe epilepsy

IB MD, MT MRCPath, OD Wiestler - Brain pathology, 2002 - Wiley Online Library
Ammon's horn sclerosis (AHS) is the major neuropathological substrate in patients with
temporal lobe epilepsy (TLE). Histopathological hallmarks include segmental loss of …

Surgery for malformations of cortical development causing epilepsy

SM Sisodiya - Brain, 2000 - academic.oup.com
Malformations of cortical development (MCD) are responsible for many cases of refractory
epilepsy in adults and children. The results of surgical treatment are difficult to assess from …

Focal cortical dysplasia: neuropathological subtypes, EEG, neuroimaging and surgical outcome

L Tassi, N Colombo, R Garbelli, S Francione… - Brain, 2002 - academic.oup.com
Since the original description by Taylor, the term focal cortical dysplasia has been used to
refer to a wide range of alterations of the cortical mantle. More recently, these conditions …

Prognostic factors and outcome after different types of resection for temporal lobe epilepsy

H Clusmann, J Schramm, T Kral, C Helmstaedter… - Journal of …, 2002 - thejns.org
Object. It is unknown whether different resection strategies for temporal lobe epilepsy (TLE)
produce alterations in seizure control or neuropsychological performance. Methods. A series …

Hippocampal volume in normal aging and traumatic brain injury.

ED Bigler, DD Blatter, CV Anderson… - American Journal …, 1997 - Am Soc Neuroradiology
PURPOSE To present a normative database of hippocampal and temporal horn volume and
to clarify the relationship between these measures and cognitive outcome in patients with …

Different features of histopathological subtypes of pediatric focal cortical dysplasia

P Krsek, B Maton, B Korman… - Annals of Neurology …, 2008 - Wiley Online Library
Objective Focal cortical dysplasia (FCD) is the most frequent pathological finding in pediatric
epilepsy surgery patients. Several histopathological types of FCD are distinguished. The aim …

Long-term outcome of epilepsy surgery among 399 patients with nonlesional seizure foci including mesial temporal lobe sclerosis

AA Cohen-Gadol, BG Wilhelmi, F Collignon… - Journal of …, 2006 - thejns.org
Object The authors reviewed the long-term outcome of focal resection in a large group of
patients who had intractable partial nonlesional epilepsy, including mesial temporal lobe …

Does the cause of localisation‐related epilepsy influence the response to antiepileptic drug treatment?

LJ Stephen, P Kwan, MJ Brodie - Epilepsia, 2001 - Wiley Online Library
Purpose: We investigated the response to antiepileptic drug (AED) therapy in patients with
localisation‐related epilepsy associated with different underlying causes. Methods: Five …

Different presurgical characteristics and seizure outcomes in children with focal cortical dysplasia type I or II

P Krsek, T Pieper, A Karlmeier, M Hildebrandt… - …, 2009 - Wiley Online Library
Purpose: Cortical dysplasia (FCD) is a frequent cause of epilepsy in childhood. Two major
pathological variants are distinguished, FCD type I and II. The aim of the study was to …

[HTML][HTML] In vitro formation of a secondary epileptogenic mirror focus by interhippocampal propagation of seizures

I Khalilov, GL Holmes, Y Ben-Ari - Nature neuroscience, 2003 - nature.com
We have determined whether seizures generate an epileptogenic focus in distal structures
using an in vitro preparation composed of three independent chambers that accommodate …