Ecology and evolution of Mycobacterium tuberculosis

S Gagneux - Nature Reviews Microbiology, 2018 - nature.com
Tuberculosis (TB) is the number one cause of human death due to an infectious disease.
The causative agents of TB are a group of closely related bacteria known as the …

[HTML][HTML] Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers …

RD Kanabalan, LJ Lee, TY Lee, PP Chong… - Microbiological …, 2021 - Elsevier
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …

RASP 4: ancestral state reconstruction tool for multiple genes and characters

Y Yu, C Blair, X He - Molecular biology and evolution, 2020 - academic.oup.com
With the continual progress of sequencing techniques, genome-scale data are increasingly
used in phylogenetic studies. With more data from throughout the genome, the relationship …

Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history

M Coscolla, S Gagneux, F Menardo… - Microbial …, 2021 - microbiologyresearch.org
Human tuberculosis (TB) is caused by members of the Mycobacterium tuberculosis complex
(MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis …

[HTML][HTML] Transcontinental spread and evolution of Mycobacterium tuberculosis W148 European/Russian clade toward extensively drug resistant tuberculosis

M Merker, JP Rasigade, M Barbier, H Cox… - Nature …, 2022 - nature.com
Transmission-driven multi-/extensively drug resistant (M/XDR) tuberculosis (TB) is the
largest single contributor to human mortality due to antimicrobial resistance. A few major …

Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study

J van Ingen, TA Kohl, K Kranzer, B Hasse… - The Lancet Infectious …, 2017 - thelancet.com
Background Since 2013, over 100 cases of Mycobacterium chimaera prosthetic valve
endocarditis and disseminated disease were notified in Europe and the USA, linked to …

[HTML][HTML] The relative transmission fitness of multidrug-resistant Mycobacterium tuberculosis in a drug resistance hotspot

C Loiseau, EM Windels, SM Gygli, L Jugheli… - Nature …, 2023 - nature.com
Multidrug-resistant tuberculosis (MDR-TB) is among the most frequent causes of death due
to antimicrobial resistance. Although only 3% of global TB cases are MDR, geographical …

[HTML][HTML] Population structure, biogeography and transmissibility of Mycobacterium tuberculosis

L Freschi, R Vargas Jr, A Husain, SMM Kamal… - Nature …, 2021 - nature.com
Mycobacterium tuberculosis is a clonal pathogen proposed to have co-evolved with its
human host for millennia, yet our understanding of its genomic diversity and biogeography …

Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam

KE Holt, P McAdam, PVK Thai, NTT Thuong, DTM Ha… - Nature …, 2018 - nature.com
To examine the transmission dynamics of Mycobacterium tuberculosis (Mtb) isolated from
tuberculosis patients in Ho Chi Minh City, Vietnam, we sequenced the whole genomes of …

[HTML][HTML] A new phylogenetic framework for the animal-adapted Mycobacterium tuberculosis complex

D Brites, C Loiseau, F Menardo, S Borrell… - Frontiers in …, 2018 - frontiersin.org
Tuberculosis (TB) affects humans and other animals and is caused by bacteria from the
Mycobacterium tuberculosis complex (MTBC). Previous studies have shown that there are at …