At the current state of development of chemistry, it appears easier to synthesize a compound
with a definite chemical structure than with a certain required property. Usually, reaction …

Advances in the theory of gradient liquid chromatography and their practical impacts are
reviewed. Theoretical models describing retention in reversed-phase, normal-phase and ion …

The current in-depth proteomics makes use of long chromatography gradient to get access
to more peptides for protein identification, resulting in covering of as many as 8000 …

Delineating its usage in separation, purification and detection processes across a variety of
disciplines, from industry to applied research, this work discusses the principles, techniques …

pH gradient reversed-phase HPLC consists of a programmed increase during the
chromatographic run of the eluting power of the mobile phase with regard to ionizable …

The measurement of physicochemical properties at an early phase of drug discovery and
development is crucial to reduce attrition rates due to poor biopharmaceutical properties …

The properties relevant to pharmacokinetics of two series of newly synthesized succinimide
derivatives have been studied. The properties under consideration have been either …

Reversed phase liquid chromatography (RPLC) is a mode of high-performance liquid
chromatography (HPLC) that employs a nonpolar stationary phase and a polar mobile …

For more than four decades, scientists and researchers have relied on the Advances in
Chromatography series for the most up-to-date information on a wide range of …

Interpretive approaches for selectivity optimisation, which are those supported by retention
models, are able to exploit efficiently the capabilities of the chromatographic system. The …