The tectum/superior colliculus as the vertebrate solution for spatial sensory integration and action

T Isa, E Marquez-Legorreta, S Grillner, EK Scott - Current Biology, 2021 - cell.com
The superior colliculus, or tectum in the case of non-mammalian vertebrates, is a part of the
brain that registers events in the surrounding space, often through vision and hearing, but …

Zebrafish behavior: opportunities and challenges

MB Orger, GG de Polavieja - Annual review of neuroscience, 2017 - annualreviews.org
A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …

The mesencephalic locomotor region recruits V2a reticulospinal neurons to drive forward locomotion in larval zebrafish

M Carbo-Tano, M Lapoix, X Jia, O Thouvenin… - Nature …, 2023 - nature.com
The mesencephalic locomotor region (MLR) is a brain stem area whose stimulation triggers
graded forward locomotion. How MLR neurons recruit downstream vsx2+(V2a) …

Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (Danio rerio)

L Cong, Z Wang, Y Chai, W Hang, C Shang, W Yang… - elife, 2017 - elifesciences.org
The internal brain dynamics that link sensation and action are arguably better studied during
natural animal behaviors. Here, we report on a novel volume imaging and 3D tracking …

Video-rate volumetric functional imaging of the brain at synaptic resolution

R Lu, W Sun, Y Liang, A Kerlin, J Bierfeld… - Nature …, 2017 - nature.com
Neurons and neural networks often extend hundreds of micrometers in three dimensions.
Capturing the calcium transients associated with their activity requires volume imaging …

Structure of the zebrafish locomotor repertoire revealed with unsupervised behavioral clustering

JC Marques, S Lackner, R Félix, MB Orger - Current Biology, 2018 - cell.com
An important concept in ethology is that complex behaviors can be constructed from a set of
basic motor patterns. Identifying the set of patterns available to an animal is key to making …

Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion

TW Dunn, Y Mu, S Narayan, O Randlett, EA Naumann… - Elife, 2016 - elifesciences.org
In the absence of salient sensory cues to guide behavior, animals must still execute
sequences of motor actions in order to forage and explore. How such successive motor …

[HTML][HTML] From whole-brain data to functional circuit models: the zebrafish optomotor response

EA Naumann, JE Fitzgerald, TW Dunn, J Rihel… - Cell, 2016 - cell.com
Detailed descriptions of brain-scale sensorimotor circuits underlying vertebrate behavior
remain elusive. Recent advances in zebrafish neuroscience offer new opportunities to …

Pan-neuronal calcium imaging with cellular resolution in freely swimming zebrafish

DH Kim, J Kim, JC Marques, A Grama… - Nature …, 2017 - nature.com
Calcium imaging with cellular resolution typically requires an animal to be tethered under a
microscope, which substantially restricts the range of behaviors that can be studied. To …

Brainstem circuits encoding start, speed, and duration of swimming in adult zebrafish

EM Berg, L Mrowka, M Bertuzzi, D Madrid, LD Picton… - Neuron, 2023 - cell.com
The flexibility of locomotor movements requires an accurate control of their start, duration,
and speed. How brainstem circuits encode and convey these locomotor parameters remains …