IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Endometrial immune dysfunction in recurrent pregnancy loss

C Ticconi, A Pietropolli, N Di Simone… - International journal of …, 2019 - mdpi.com
Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …

Obesity and recurrent miscarriage: A systematic review and meta‐analysis

MB Cavalcante, M Sarno, AB Peixoto… - Journal of Obstetrics …, 2019 - Wiley Online Library
The aim of this study is to perform a systematic review and meta‐analysis on the relationship
between excess weight and risk of recurrent pregnancy loss (RPL) and to highlight the …

The update immune-regulatory role of pro-and anti-inflammatory cytokines in recurrent pregnancy losses

X Yang, Y Tian, L Zheng, T Luu… - International journal of …, 2022 - mdpi.com
Recurrent pregnancy losses (RPL) is a common reproductive disorder with various
underlying etiologies. In recent years, rapid progress has been made in exploring the …

The influence of COVID-19 infection-associated immune response on the female reproductive system

M Saadedine, M El Sabeh, MA Borahay… - Biology of …, 2023 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) is a multi-system disease that has led to a
pandemic with unprecedented ramifications. The pandemic has challenged scientists for the …

[HTML][HTML] Role of transforming growth factor-β1 in regulating fetal-maternal immune tolerance in normal and pathological pregnancy

D Yang, F Dai, M Yuan, Y Zheng, S Liu… - Frontiers in …, 2021 - frontiersin.org
Transforming growth factor-β (TGF-β) is composed of three isoforms, TGF-β1, TGF-β2, and
TGF-β3. TGF-β1 is a cytokine with multiple biological functions that has been studied …

Distinct pattern of Th17/Treg cells in pregnant women with a history of unexplained recurrent spontaneous abortion

J Qian, N Zhang, J Lin, C Wang, X Pan, L Chen… - Bioscience …, 2018 - jstage.jst.go.jp
The aim of the current study was to determine the pattern of immune cells and related
functional molecules in peripheral blood and at the maternal-fetal interface in women with …

DNA methylation and recurrent pregnancy loss: a mysterious compass?

Q Zhou, Y Xiong, B Qu, A Bao, Y Zhang - Frontiers in immunology, 2021 - frontiersin.org
Recurrent pregnancy loss (RPL) is a common and severe pathological pregnancy, whose
pathogenesis is not fully understood. With the development of epigenetics, the study of DNA …

T helper cell immunity in pregnancy and influence on autoimmune disease progression

JJ Graham, MS Longhi, MA Heneghan - Journal of autoimmunity, 2021 - Elsevier
Pregnancy presents the maternal immune system with a unique immunological challenge
since it has to defend against pathogens while tolerating paternal allo-antigens expressed …

An overview of the therapeutic effects of curcumin in reproductive disorders with a focus on the antiinflammatory and immunomodulatory activities

B Saifi, SM Haftcheshmeh, M Feligioni… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin, the polyphenolic compound obtained from turmeric, has several pharmacological
properties. These properties include antioxidant, antimicrobial, anti‐angiogenic …