Chronic obstructive pulmonary disease (COPD) is a debilitating heterogeneous disease
characterised by unregulated proteolytic destruction of lung tissue mediated via a protease …

SERPIN (serine proteinase inhibitors) is an acronym for the superfamily of structurally similar
proteins found in animals, plants, bacteria, viruses, and archaea. Over 1500 SERPINs are …

Antithrombin is a key inhibitor of the coagulation cascade, but it may also function as an anti-
inflammatory, anti-angiogenic, anti-viral and anti-apoptotic protein. Here, we report a novel …

Urinary proteins serve as indicators of various conditions in human normal physiology and
disease pathology. Using mass spectrometry proteome analysis, the permanent constituent …

Background The application of advanced imaging technologies for identifying pancreatic
cysts has become widespread. However, accurately differentiating between low-grade …

The membrane-anchored serine proteases are a unique group of trypsin-like serine
proteases that are tethered to the cell surface via transmembrane domains or glycosyl …

Protein C inhibitor (PCI) is a serpin with broad protease reactivity. It binds
glycosaminoglycans and certain phospholipids that can modulate its inhibitory activity. PCI …

Primary bovine intestinal epithelial cells (PBIECs) are an important model for studying the
molecular and pathogenic mechanisms of diseases affecting the bovine intestine. It is …

Human protein C inhibitor (PCI, SerpinA5) was first identified in 1980 as an inhibitor of
activated protein C (APC). It was soon recognized that the secreted 57 kDa glycoprotein …

Защита диссертации состоется «8» июля 2015 г. В 10 часов на заседании
диссертационного совета Д 002.111. 01, созданного на базе Федерального …