The skeletal system is essential for preserving body structure and facilitating mobility;
however, bone diseases frequently result in significant disabilities, necessitating the …

Monocytes activated by pro-inflammatory signals adhere to the vascular endothelium and
migrate from the bloodstream to the tissue ultimately differentiating into macrophages. Cell …

The innate immune system forms a crucial defense mechanism of the human body against
infections and foreign objects, orchestrates wound healing, and restores tissue homeostasis …

Liquid biopsies have been receiving tremendous attention for their potential to reshape
cancer management. Though current studies of cancer liquid biopsy primarily fucus on …

Macrophages are innate immune cells that are known for their extreme plasticity, enabling
diverse phenotypes that lie on a continuum. In a simplified model, they switch between pro …

Macrophage phagocytosis is critical for the immune response, homeostasis regulation, and
tissue repair. This intricate process involves complex changes in cell morphology …

Nuclear receptor Nur77 plays a pivotal role in immune regulation across various tissues,
influencing pro-inflammatory signaling pathways and cellular metabolism. While cellular …

Immune cells continuously adapt their mechanical properties for proper circulation and
elicitation of immune responses. Here, we provide a step-by-step protocol for probing the …

Background and aims Obesity-induced chronic inflammation and metabolic abnormalities
are highly relevant to the functional dysregulation of macrophages, especially under obese …

Macrophages are innate immune cells that are known for their diverse phenotypes and
plasticity. They switch between pro-inflammatory (M1) and anti-inflammatory/pro-fibrotic (M2) …