Candida Biofilms: Threats, Challenges, and Promising Strategies

M Cavalheiro, MC Teixeira - Frontiers in medicine, 2018 - frontiersin.org
Candida species are fungal pathogens known for their ability to cause superficial and
systemic infections in the human host. These pathogens are able to persist inside the host …

Candida albicans targets that potentially synergize with fluconazole

H Lu, M Shrivastava, M Whiteway… - Critical reviews in …, 2021 - Taylor & Francis
Fluconazole has characteristics that make it widely used in the clinical treatment of C.
albicans infections. However, fluconazole has only a fungistatic activity in C. albicans …

Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities

X Wu, Y Xia, F He, C Zhu, W Ren - Microbiome, 2021 - Springer
Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other
microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology …

Fungal quorum sensing molecules: role in fungal morphogenesis and pathogenicity

T Wongsuk, P Pumeesat… - Journal of Basic …, 2016 - Wiley Online Library
When microorganisms live together in high numbers, they need to communicate with each
other. To achieve cell–cell communication, microorganisms secrete molecules called …

[HTML][HTML] Quercetin assists fluconazole to inhibit biofilm formations of fluconazole-resistant Candida albicans in in vitro and in vivo antifungal managements of …

M Gao, H Wang, LJ Zhu - Cellular Physiology and Biochemistry, 2016 - karger.com
Background: Vulvovaginal candidiasis (VVC) is a common gynecological disease. Candida
albicans is believed to be mainly implicated in VVC occurrence, the biofilm of which is one of …

UPLC-ESI-MS/MS profiling of the underground parts of common Iris species in relation to their anti-virulence activities against Staphylococcus aureus

MM Okba, PMA Baki, M Abu-Elghait… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance The use of plant extracts and their phytochemicals as
candidates for targeting the microbial resistance inhibition is increasingly focused in last …

Fungal Quorum-Sensing Molecules: A Review of Their Antifungal Effect against Candida Biofilms

R Kovács, L Majoros - Journal of Fungi, 2020 - mdpi.com
The number of effective therapeutic strategies against biofilms is limited; development of
novel therapies is urgently needed to treat a variety of biofilm-associated infections. Quorum …

Farnesol signalling in Candida albicans – more than just communication

M Polke, I Leonhardt, O Kurzai… - Critical Reviews in …, 2018 - Taylor & Francis
Candida albicans is a successful colonizer of the human host, which can, under certain
circumstances cause a range of clinically diverse infections. Important virulence-associated …

Combination therapy to treat fungal biofilm-based infections

J Tits, BPA Cammue, K Thevissen - International Journal of Molecular …, 2020 - mdpi.com
An increasing number of people is affected by fungal biofilm-based infections, which are
resistant to the majority of currently-used antifungal drugs. Such infections are often caused …

Effects of tyrosol and farnesol on Candida albicans biofilm

S Sebaa, Z Boucherit-Otmani… - Molecular medicine …, 2019 - spandidos-publications.com
The present in vitro study examined the effects of the quorum-sensing molecules farnesol
and tyrosol on the development of Candida albicans biofilm in order to elucidate their role as …