Infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-
negative bacteria (GNB), including carbapenem-resistant (CR) Enterobacterales (CRE; …

Plasmids are universally present in bacteria and play key roles in the dissemination of
genes such as antibiotic resistance determinants. Major concepts in Plasmid Biology derive …

Carbapenemase-producing Enterobacterales (CPE) infection control practices are based on
the paradigm that detected carriers in the hospital transmit to other patients who stay in the …

Carbapenemase gene-positive (CP) Gram-negative bacilli are of significant clinical and
public health concern. Their rapid detection and containment are critical to preventing their …

Background An outbreak of VIM carbapenemase-expressing Enterobacter cloacae complex
occurred between March and October 2020 in an intensive care unit (ICU) of a tertiary care …

Plasmids are the main driving forces for the rapid dissemination of bla NDM-1. In recent
years, bla NDM-1-carrying fusion plasmids have been frequently reported. However, the …

Background Current microbiological methods lack the resolution to accurately identify
multidrug-resistant organism (MDRO) transmission, however, whole genome sequencing …

Summary Background Between 2018 and 2022, a Belgian tertiary care hospital faced a
growing issue with acquiring carbapenemase-producing organisms (CPO), mainly VIM …

Wastewater has a major role in antimicrobial resistance (AMR) dynamics and public health.
The impact on AMR of wastewater flux at the community-hospital interface in low-and middle …

Carbapenem-resistant Enterobacteriaceae (CRE) infections, high in morbidity and mortality,
pose serious clinical challenges due to limited treatment options. A previous CRE …