Microfluidic formulation of nanoparticles for biomedical applications

SJ Shepherd, D Issadore, MJ Mitchell - Biomaterials, 2021 - Elsevier
Nanomedicine has made significant advances in clinical applications since the late-20th
century, in part due to its distinct advantages in biocompatibility, potency, and novel …

[HTML][HTML] Emerging non-viral vectors for gene delivery

C Wang, C Pan, H Yong, F Wang, T Bo, Y Zhao… - Journal of …, 2023 - Springer
Gene therapy holds great promise for treating a multitude of inherited and acquired diseases
by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit …

[HTML][HTML] Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

Z Vinarov, B Abrahamsson, P Artursson… - Advanced Drug Delivery …, 2021 - Elsevier
Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …

Cyclodextrin based natural nanostructured carbohydrate polymers as effective non-viral siRNA delivery systems for cancer gene therapy

H Mousazadeh, Y Pilehvar-Soltanahmadi… - Journal of Controlled …, 2021 - Elsevier
Short interfering RNAs (siRNAs), as small non-coding RNA fragments, are one of the widely
studied RNAi inducers for gene modulations. The reasonably designed siRNA probes …

Macrocyclic‐Amphiphile‐Based Self‐Assembled Nanoparticles for Ratiometric Delivery of Therapeutic Combinations to Tumors

Z Zhang, YX Yue, L Xu, Y Wang, WC Geng… - Advanced …, 2021 - Wiley Online Library
Combination chemotherapy refers to the use of multiple drugs to treat cancer. In this therapy,
the optimal ratio of the drugs is essential to achieve drug synergism and the desired …

[HTML][HTML] A review on curcumin-loaded electrospun nanofibers and their application in modern medicine

S Mitra, T Mateti, S Ramakrishna, A Laha - Jom, 2022 - Springer
Herbal drugs are safe and show significantly fewer side effects than their synthetic
counterparts. Curcumin (an active ingredient primarily found in turmeric) shows therapeutic …

[HTML][HTML] History of cyclodextrin-based polymers in food and pharmacy: A review

M Petitjean, IX García-Zubiri, JR Isasi - Environmental Chemistry Letters, 2021 - Springer
Cyclodextrins are glucose macrocycles whose inclusional capabilities towards non-polar
solutes can be modulated with the help of other macrostructures. The incorporation of …

Biomaterial‐based gene therapy

Y Yu, Y Gao, L He, B Fang, W Ge, P Yang, Y Ju… - MedComm, 2023 - Wiley Online Library
Gene therapy, a medical approach that involves the correction or replacement of defective
and abnormal genes, plays an essential role in the treatment of complex and refractory …

[HTML][HTML] An updated overview of cyclodextrin-based drug delivery systems for cancer therapy

DN Păduraru, AG Niculescu, A Bolocan, O Andronic… - Pharmaceutics, 2022 - mdpi.com
Encompassing a group of complex and heterogeneous diseases, cancer continues to be a
challenge for patients and healthcare systems worldwide. Thus, it is of vital importance to …

Anticancer potential of curcumin-cyclodextrin complexes and their pharmacokinetic properties

M Shahriari, P Kesharwani, TP Johnston… - International Journal of …, 2023 - Elsevier
Cancer is one of the most common diseases throughout the world, with many treatment
modalities currently being used, and new treatment strategies being sought. Most …