Air–Liquid Interface In Vitro Models for Respiratory Toxicology Research: Consensus Workshop and Recommendations
In vitro air–liquid interface (ALI) cell culture models can potentially be used to assess
inhalation toxicology endpoints and are usually considered, in terms of relevancy, between …
inhalation toxicology endpoints and are usually considered, in terms of relevancy, between …
[HTML][HTML] In vitro and ex vivo models in inhalation biopharmaceutical research—advances, challenges and future perspectives
Oral inhalation results in pulmonary drug targeting and thereby reduces systemic side
effects, making it the preferred means of drug delivery for the treatment of respiratory …
effects, making it the preferred means of drug delivery for the treatment of respiratory …
Hazard and risk assessment of a nanoparticulate cerium oxide-based diesel fuel additive—a case study
Envirox is a scientifically and commercially proven diesel fuel combustion catalyst based on
nanoparticulate cerium oxide and has been demonstrated to reduce fuel consumption …
nanoparticulate cerium oxide and has been demonstrated to reduce fuel consumption …
A toxicological evaluation of inhaled solid lipid nanoparticles used as a potential drug delivery system for the lung
M Nassimi, C Schleh, HD Lauenstein, R Hussein… - European Journal of …, 2010 - Elsevier
Inhalation is a non-invasive approach for both local and systemic drug delivery. This study
aimed to define the therapeutic window for solid lipid nanoparticles (SLNs) as a drug …
aimed to define the therapeutic window for solid lipid nanoparticles (SLNs) as a drug …
[PDF][PDF] In vitro models of inhalation toxicity and disease
K BeruBe, M Aufderheide, D Breheny… - … to laboratory animals, 2009 - academia.edu
Background The respiratory system represents a major portal of entry for xenobiotics into the
body, whether they be intentionally administered as in the case of drugs and anaesthetics …
body, whether they be intentionally administered as in the case of drugs and anaesthetics …
Toxicity Assessment of Industrial Chemicals and Airborne Contaminants: Transition from In Vivo to In Vitro Test Methods: A Review
Exposure to occupational and environmental contaminants is a major contributor to human
health problems. Inhalation of gases, vapors, aerosols, and mixtures of these can cause a …
health problems. Inhalation of gases, vapors, aerosols, and mixtures of these can cause a …
Precision cut lung slices as an efficient tool for in vitro lung physio-pharmacotoxicology studies
JP Morin, JM Baste, A Gay, C Crochemore… - Xenobiotica, 2013 - Taylor & Francis
1. We review the specific approaches for lung tissue slices preparation and incubation
systems and the research application fields in which lung slices proved to be a very efficient …
systems and the research application fields in which lung slices proved to be a very efficient …
In vitro exposures in diesel exhaust atmospheres: resuspension of PM from filters versus direct deposition of PM from air
KM Lichtveld, SM Ebersviller, KG Sexton… - … science & technology, 2012 - ACS Publications
One of the most widely used in vitro particulate matter (PM) exposures methods is the
collection of PM on filters, followed by resuspension in a liquid medium, with subsequent …
collection of PM on filters, followed by resuspension in a liquid medium, with subsequent …
In vitro lung slices: a powerful approach for assessment of lung pathophysiology
TA Liberati, MR Randle, LA Toth - Expert review of molecular …, 2010 - Taylor & Francis
This review summarizes the existing literature on the use of in vitro lung slices to study
pulmonary physiology, pharmacology, pathogenesis and toxicity. Since in vitro lung slices …
pulmonary physiology, pharmacology, pathogenesis and toxicity. Since in vitro lung slices …
Direct exposure methods for testing native atmospheres
M Aufderheide - Experimental and Toxicologic Pathology, 2005 - Elsevier
In vitro studies of adverse cellular effects induced by inhalable substances face a number of
problems due to the difficulties in exposing cultured cells of the respiratory tract directly to …
problems due to the difficulties in exposing cultured cells of the respiratory tract directly to …