Aims and Background This paper deals with the clinical significance of the
immunohistochemical expression of MAGE-A1, MAGE-A3/4 and NY-ESO-1 antigens in …

Cancer testis antigens (CTAs) are of clinical interest as biomarkers and present valuable
targets for immunotherapy. To comprehensively characterize the CTA landscape of non …

Non-small cell lung cancer (NSCLC) is the biggest cancer killer in the United States and
worldwide. In 2011, there are estimated to be 221,130 new cases of lung cancer in the …

Purpose: To determine the immunologic effects of neoadjuvant chemotherapy plus
ipilimumab in early-stage non–small cell lung cancer (NSCLC) patients. Experimental …

Background Cancer/testis antigens (CTAs) were first discovered as immunogenic targets
normally expressed in germline cells, but differentially expressed in a variety of human …

High hydrostatic pressure (HHP) induces immunogenic death of tumor cells which confer
protective anti-tumor immunity in vivo. Moreover, DC pulsed with HHP-treated tumor cells …

Background Specific immune response is a hallmark of cancer immunotherapy and shared
tumor-associated antigens (TAAs) are important targets. Recent advances using combined …

Context.—Human telomerase reverse transcriptase (hTERT), an enzyme that enables cells
to overcome replicative senescence and to divide indefinitely, is overexpressed in many …

Existing evidence regarding spontaneous anti-survivin humoral responses in lung cancer is
inconclusive. Moreover, despite that cancer cell death elicited by radiotherapy and some …

Purpose Glioblastoma multiforme (GBM) is a highly malignant tumor of the central nervous
system. Although primary GBM patients receive extensive therapies, tumors may recur within …