Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …

Acetate is regarded as a promising carbon feedstock in biological production owing to its
possible derivation from C 1 gases such as CO, CO 2 and methane. To best use of acetate …

During aerobic growth on glucose, Escherichia coli excretes acetate, a mechanism called
“overflow metabolism.” At high concentrations, the secreted acetate inhibits growth. Several …

2017 marks the 60th anniversary of Krebs' seminal paper on the glyoxylate shunt (and
coincidentally, also the 80th anniversary of his discovery of the citric acid cycle). Sixty years …

In E scherichia coli, acetylation of proteins at lysines depends largely on a non‐enzymatic
acetyl phosphate‐dependent mechanism. To assess the functional significance of this post …

Response regulators function as the output components of two-component systems, which
couple the sensing of environmental stimuli to adaptive responses. Response regulators …

ABSTRACT N ε-Lysine acetylation is now recognized as an abundant posttranslational
modification (PTM) that influences many essential biological pathways. Advancements in …

Lysine residues can be post-translationally modified by various acyl modifications in
bacteria and eukarya. Here, we showed that two major acyl modifications, acetylation and …

Posttranslational modifications, such as N ε-lysine acetylation, regulate protein function. N ε-
lysine acetylation can occur either nonenzymatically or enzymatically. The nonenzymatic …

Posttranslational modification of a protein, either alone or in combination with other
modifications, can control properties of that protein, such as enzymatic activity, localization …