The first report demonstrating that prolonged endurance exercise promotes oxidative stress
in humans was published more than 4 decades ago. Since this discovery, many ensuing …

The cells secrete extracellular vesicles (EV) that may have an endosomal origin, or from
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …

Quercetin, a typical flavonoid, possesses diverse biochemical and physiological actions,
including antiplatelet, estrogenic, and anti-inflammatory properties. This review mainly …

World population growth and aging are posing unprecedented challenges in sustaining the
health of 9.1 billion people that will be occupying the planet by 2050. Although …

The prevalence of diabetes has dramatically increased worldwide due to the vast increase
in the obesity rate. Diabetic nephropathy is one of the major complications of type 1 and type …

The observation that muscular exercise is associated with oxidative stress in humans was
first reported over 30years ago. Since this initial report, numerous studies have confirmed …

Ischemia/reperfusion, which is characterized by deficient oxygen supply and subsequent
restoration of blood flow, can cause irreversible damages to tissue. Mechanisms contributing …

This study was to investigate whether sulforaphane (SFN) can prevent diabetic
cardiomyopathy. Type 1 diabetes was induced in FVB mice by multiple intraperitoneal …

Diabetic wounds represent a significant healthcare burden and are characterized by
impaired wound healing due to increased oxidative stress and persistent inflammation. We …

Background Diabetic wounds have become one of the most challenging public health
issues of the 21st century, yet there is no effective treatment available. We have previously …