Systematic review and meta-analysis of the clinical utility of Enhanced Recovery After Surgery pathways in adult spine surgery

Z Pennington, E Cottrill, D Lubelski… - … of Neurosurgery: Spine, 2020 - thejns.org
OBJECTIVE Spine surgery has been identified as a significant source of healthcare
expenditures in the United States. Prolonged hospitalization has been cited as one source …

The association of thromboembolic complications and the use of tranexamic acid during resection of intracranial meningiomas: systematic review and meta-analysis of …

A Nguyen, NJ Brown, J Gendreau, BA Nguyen… - Journal of …, 2023 - thejns.org
OBJECTIVE Antifibrinolytics, such as tranexamic acid (TXA), have been shown to decrease
intraoperative blood loss across multiple surgical disciplines. However, they carry the …

[HTML][HTML] Influence of tranexamic acid use on venous thromboembolism risk in patients undergoing surgery for spine tumors

Z Pennington, J Ehresman, A Schilling… - … of Neurosurgery: Spine, 2021 - thejns.org
OBJECTIVE Patients with spine tumors are at increased risk for both hemorrhage and
venous thromboembolism (VTE). Tranexamic acid (TXA) has been advanced as a potential …

Cost-effectiveness of adult spinal deformity surgery

AM Alvarado, BA Schatmeyer… - Global Spine …, 2021 - journals.sagepub.com
Study Design: Review article. Objective: A review of the literature evaluating the cost-
effectiveness of undergoing adult spinal deformity surgery and potential avenues for …

Single dose of tranexamic acid effectively reduces blood loss in patients undergoing spine surgery: a prospective randomized controlled trial

A Reyes-Sánchez, A Domínguez-Soto… - World Neurosurgery, 2023 - Elsevier
Objective To evaluate the efficacy of oral administration of tranexamic acid (TXA) in spine
surgery to achieve blood loss reduction. Methods Sixty patients undergoing major surgery of …

A clinical calculator for predicting intraoperative blood loss and transfusion risk in spine tumor patients

Z Pennington, J Ehresman, J Feghali, A Schilling… - The Spine Journal, 2021 - Elsevier
BACKGROUND CONTEXT Surgery for vertebral column tumors is commonly associated
with intraoperative blood loss (IOBL) exceeding 2 liters and the need for transfusion of …

[HTML][HTML] Tranexamic acid is associated with decreased transfusion, hospital length of stay, and hospital cost in simultaneous bilateral total knee arthroplasty

RS D'Souza, CM Duncan, DR Whiting… - Bosnian journal of …, 2021 - ncbi.nlm.nih.gov
Tranexamic acid (TXA) reduces blood loss and transfusion rates in unilateral total knee
arthroplasty (TKA), but there is limited data regarding its efficacy in bilateral TKA. This study …

Predicting nonroutine discharge in patients undergoing surgery for vertebral column tumors

J Ehresman, Z Pennington, J Feghali… - … of Neurosurgery: Spine, 2020 - thejns.org
OBJECTIVE More than 8000 patients are treated annually for vertebral column tumors, of
whom roughly two-thirds will be discharged to an inpatient facility (nonroutine discharge) …

[HTML][HTML] Safety and efficacy of high-dose tranexamic acid in spine surgery: a retrospective single-institution series

NJ Brown, Z Pennington, AS Himstead, CY Yang… - World Neurosurgery, 2023 - Elsevier
Objective Currently, tranexamic acid (TXA) is the most widely used antifibrinolytic agent in
spine surgery and has been proven to reduce perioperative blood loss. However, the safety …

[HTML][HTML] The impact of tranexamic acid on perioperative outcomes in urological surgeries: A systematic review and meta-analysis

J Kim, A Alrumaih, C Donnelly, M Uy… - Canadian Urological …, 2023 - ncbi.nlm.nih.gov
METHODS A comprehensive search was conducted from the following databases: PubMed,
Embase, Cochrane Library, and Web of Science. Two reviewers performed title and abstract …