Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

Recent trends in preparation, investigation and application of polysaccharide-based chiral stationary phases for separation of enantiomers in high-performance liquid …

B Chankvetadze - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
This review article summarizes the recent developments in preparation, investigation and
application of polysaccharide-based chiral stationary phases for the separation of …

Van't Hoff analysis in chiral chromatography

LD Asnin, MV Stepanova - Journal of separation science, 2018 - Wiley Online Library
The present review discusses the theory and application of van't Hoff analysis in chiral
chromatography, with main focus on liquid chromatography. The topics considered include …

State-of-the-art enantioseparations of natural and unnatural amino acids by high-performance liquid chromatography

I Ilisz, A Péter, W Lindner - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
This review discusses recent publications on the separation and analysis of natural and
unnatural amino acid enantiomers by liquid chromatography. Focus is placed on …

Enantioseparation and molecular docking study of selected chiral pharmaceuticals on a commercialized phenylcarbamate-β-cyclodextrin column using polar organic …

M Dobó, M Ádám, B Fiser, LA Papp, G Dombi… - Scientific Reports, 2023 - nature.com
The chiral separation capability of Chiral-CD-Ph column, containing phenylcarbamate-β-
cyclodextrin as the chiral selector in polar organic mode was investigated. A total of twenty …

The effect of temperature on the separation of enantiomers with coated and covalently immobilized polysaccharide-based chiral stationary phases

I Matarashvili, G Kobidze, A Chelidze, G Dolidze… - … of Chromatography A, 2019 - Elsevier
This article describes our attempt to re-visit the role of temperature in the separation of
enantiomers with polysaccharide-based chiral columns in high-performance liquid …

Liquid chromatographic enantiomer separations applying chiral ion-exchangers based on Cinchona alkaloids

I Ilisz, A Bajtai, W Lindner, A Péter - Journal of Pharmaceutical and …, 2018 - Elsevier
As the understanding of the various biological actions of compounds with different
stereochemistry has grown, the necessity to develop methods for the analytical qualification …

Chiral stationary phases based on small molecules: An update of the last 17 years

C Fernandes, YZ Phyo, AS Silva… - Separation & …, 2018 - Taylor & Francis
A literature survey covering the report on Pirkle-type chiral stationary phases (CSPs) from
January 2000 to March 2017 is presented in this review. More than 200 CSPs comprising …

Simultaneous determination of penthiopyrad enantiomers and its metabolite in vegetables, fruits, and cereals using ultra‐high performance liquid chromatography …

T Zhao, Y Liu, H Liang, L Li, K Shi… - Journal of …, 2022 - Wiley Online Library
Penthiopyrad is a novel succinate dehydrogenase inhibitor that has one chiral center and
exists a metabolite, 1‐methyl‐3‐trifluoromethyl‐1H‐pyrazole‐4‐carboxamide in its residue …

Enantioselective human serum albumin binding of apremilast: liquid chromatographic, fluorescence and molecular docking study

G Dombi, P Horváth, B Fiser, A Mirzahosseini… - International Journal of …, 2023 - mdpi.com
The interaction between human serum albumin (HSA) and apremilast (APR), a novel
antipsoriatic drug, was characterized by multimodal analytical techniques including high …