Dynamic immunoediting by macrophages in homologous recombination deficiency-stratified pancreatic ductal adenocarcinoma
WF Hong, F Zhang, N Wang, JM Bi, DW Zhang… - Drug Resistance …, 2024 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease, notably resistant to existing
therapies. Current research indicates that PDAC patients deficient in homologous …
therapies. Current research indicates that PDAC patients deficient in homologous …
Overexpression of ABCC1 and ABCG2 confers resistance to talazoparib, a poly (ADP-Ribose) polymerase inhibitor
Aims The overexpression of ABC transporters on cancer cell membranes is one of the most
common causes of multidrug resistance (MDR). This study investigates the impact of ABCC1 …
common causes of multidrug resistance (MDR). This study investigates the impact of ABCC1 …
Butterfly Effect in Cytarabine: Combined NMR-NQR Experiment, Solid-State Computational Modeling, Quantitative Structure-Property Relationships and Molecular …
JN Latosińska, M Latosińska, J Seliger, V Žagar… - Pharmaceuticals, 2024 - mdpi.com
Cytarabine (Ara-C) is a synthetic isomer of cytidine that differs from cytidine and
deoxycytidine only in the sugar. The use of arabinose instead of deoxyribose hinders the …
deoxycytidine only in the sugar. The use of arabinose instead of deoxyribose hinders the …
Development of Uniform Ribosome Display Technology Enabling Easy and Efficient Identification of Full‐Length Proteins that Interact with Bioactive Small and Large …
K Taguchi, Y Sakai, T Furuhashi, S Hara, A Wada - ChemBioChem - Wiley Online Library
Identifying target proteins that interact with bioactive molecules is indispensable for
understanding their mechanisms of action. In this study, we developed a uniform ribosome …
understanding their mechanisms of action. In this study, we developed a uniform ribosome …