[HTML][HTML] Damage-associated molecular patterns in trauma

B Relja, WG Land - European journal of trauma and emergency surgery, 2020 - Springer
Abstract In 1994, the “danger model” argued that adaptive immune responses are driven
rather by molecules released upon tissue damage than by the recognition of “strange” …

[HTML][HTML] Salivary defense proteins: their network and role in innate and acquired oral immunity

TK Fábián, P Hermann, A Beck, P Fejérdy… - International journal of …, 2012 - mdpi.com
There are numerous defense proteins present in the saliva. Although some of these
molecules are present in rather low concentrations, their effects are additive and/or …

Membranes: a meeting point for lipids, proteins and therapies

PV Escribá, JM González‐Ros, FM Goñi… - Journal of cellular …, 2008 - Wiley Online Library
• Introduction• Membrane lipid composition• Membrane lipid structure• Membrane lipid
organization‐Why so many different lipids?‐Lipid mixing and demixing‐Lateral pressure …

Heat shock proteins and immune system

MF Tsan, B Gao - Journal of Leucocyte Biology, 2009 - academic.oup.com
Heat shock proteins (HSPs) such as HSP 60 (Hsp60), Hsp70, Hsp90, and gp96, have been
reported to play important roles in antigen presentation and cross-presentation, activation of …

[HTML][HTML] Heat-shock proteins in neuroinflammation

B Dukay, B Csoboz, ME Tóth - Frontiers in pharmacology, 2019 - frontiersin.org
The heat-shock response, one of the main pro-survival mechanisms of a living organism,
has evolved as the biochemical response of cells to cope with heat stress. The most well …

Regulation of the cell biology of antigen cross-presentation

JM Blander - Annual review of immunology, 2018 - annualreviews.org
Antigen cross-presentation is an adaptation of the cellular process of loading MHC-I
molecules with endogenous peptides during their biosynthesis within the endoplasmic …

Hsp70 and its molecular role in nervous system diseases

G Turturici, G Sconzo, F Geraci - Biochemistry research …, 2011 - Wiley Online Library
Heat shock proteins (HSPs) are induced in response to many injuries including stroke,
neurodegenerative disease, epilepsy, and trauma. The overexpression of one HSP in …

Physiological functions of heat shock proteins

Q Shan, F Ma, J Wei, H Li, H Ma… - Current Protein and …, 2020 - ingentaconnect.com
Heat shock proteins (HSPs) are molecular chaperones involved in a variety of life activities.
HSPs function in the refolding of misfolded proteins, thereby contributing to the maintenance …

The chaperone balance hypothesis: The importance of the extracellular to intracellular HSP70 ratio to inflammation‐driven type 2 diabetes, the effect of exercise, and …

M Krause, TG Heck, A Bittencourt… - Mediators of …, 2015 - Wiley Online Library
Recent evidence shows divergence between the concentrations of extracellular 70 kDa heat
shock protein [eHSP70] and its intracellular concentrations [iHSP70] in people with type 2 …

[HTML][HTML] Membrane-associated stress proteins: more than simply chaperones

I Horváth, G Multhoff, A Sonnleitner, L Vígh - Biochimica et Biophysica Acta …, 2008 - Elsevier
The protein-and/or lipid-mediated association of chaperone proteins to membranes is a
widespread phenomenon and implicated in a number of physiological and pathological …