The spread of carbapenem-and polymyxin-resistant Enterobacteriaceae poses a significant
threat to public health, challenging clinicians worldwide with limited therapeutic options. This …

Klebsiella pneumoniae colonizes mucosal surfaces of healthy humans and is responsible
for one third of all Gram-negative infections in hospitalized patients. K. pneumoniae is …

Multidrug resistant Enterobacterales have become a serious global health problem, with
extended hospital stay and increased mortality. Antibiotic monotherapy has been reported …

In the past few decades, infectious diseases have become increasingly challenging to treat,
which is explained by the growing number of antibiotic-resistant bacteria. Notably …

Growing multi-drug resistance (MDR) among ESKAPE pathogens is a huge challenge.
Increased resistance to last-resort antibiotics, like colistin, has further aggravated this. Efflux …

Aim: Klebsiella pneumoniae is a threat to human health due to its carbapenem-resistance
and hypervirulent phenotype. Curcumin is a well-known antimicrobial agent. Hence, it is …

Urinary tract infections (UTI) by antibiotic resistant and virulent K. pneumoniae are a growing
concern. Understanding the genome and validating the genomic profile along with …

Like many organisms, bacteria constantly face selective pressures that act on particular
traits. However, they are also not passive actors in an evolutionary system. Host-switching …

Целта на настоящия дисертационен труд е да се проучи чувствителността и
механизмите на резистентността към бета-лактами и хинолони при клинично значими …

The study investigates the susceptibility and mechanisms of resistance to beta-lactams and
quinolones in clinically significant Klebsiella pneumoniae isolated from patients hospitalized …