Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential

I Paterni, C Granchi, JA Katzenellenbogen, F Minutolo - Steroids, 2014 - Elsevier
Estrogen receptors alpha (ERα) and beta (ERβ) are nuclear transcription factors that are
involved in the regulation of many complex physiological processes in humans. Modulation …

Evidence on the health benefits of supplemental propolis

A Braakhuis - Nutrients, 2019 - mdpi.com
Propolis is a honey-related product with reported health benefits such as improved
immunity, lowered blood pressure, treated allergies and skin conditions. A literature review …

Optimization and evaluation of propolis liposomes as a promising therapeutic approach for COVID-19

H Refaat, FM Mady, HA Sarhan, HS Rateb… - International journal of …, 2021 - Elsevier
The present work aimed to develop an optimized liposomal formulation for enhancing the
anti-viral activity of propolis against COVID-19. Docking studies were performed for certain …

Recent applications of vinyl sulfone motif in drug design and discovery

R Ahmadi, S Emami - European Journal of Medicinal Chemistry, 2022 - Elsevier
Vinyl sulfone with electrophilic character is not only a versatile building block for various
organic transformations but also is a key structural unit in a large number of biologically …

Honey bee toxicology

RM Johnson - Annual review of entomology, 2015 - annualreviews.org
Insecticides are chemicals used to kill insects, so it is unsurprising that many insecticides
have the potential to harm honey bees (Apis mellifera). However, bees are exposed to a …

Perspectives for uses of propolis in therapy against infectious diseases

A Salatino - Molecules, 2022 - mdpi.com
Propolis has gained wide popularity over the last decades in several parts of the world. In
parallel, the literature about propolis composition and biological properties increased …

Anti-viral and immunomodulatory properties of propolis: Chemical diversity, pharmacological properties, preclinical and clinical applications, and in silico potential …

N Yosri, AA Abd El-Wahed, R Ghonaim, OM Khattab… - Foods, 2021 - mdpi.com
Propolis, a resin produced by honeybees, has long been used as a dietary supplement and
folk remedy, and more recent preclinical investigations have demonstrated a large spectrum …

Polyphenol-chitosan conjugates: Synthesis, characterization, and applications

Q Hu, Y Luo - Carbohydrate polymers, 2016 - Elsevier
Chitosan, the only positively charged polysaccharide in the world, is very attractive for food,
medicinal and pharmaceutical applications because of its promising properties, including …

A review on natural antioxidants for their role in the treatment of Parkinson's disease

P Mittal, S Dhankhar, S Chauhan, N Garg… - Pharmaceuticals, 2023 - mdpi.com
The neurodegenerative condition known as Parkinson's disease (PD) is brought on by the
depletion of dopaminergic neurons in the basal ganglia, which is the brain region that …

Bioactive compounds (BACs): A novel approach to treat and prevent cardiovascular diseases

SRU Din, S Saeed, SU Khan, FA Kiani… - Current Problems in …, 2023 - Elsevier
Cardiovascular diseases (CVDs) are one of the leading disorders of serious death and
cause huge economic loss to patients and society. It is estimated that about 18 million …