Recent advances in our understanding of the mechanisms of late lung development and bronchopulmonary dysplasia

DE Surate Solaligue… - … of Physiology-Lung …, 2017 - journals.physiology.org
The objective of lung development is to generate an organ of gas exchange that provides
both a thin gas diffusion barrier and a large gas diffusion surface area, which concomitantly …

Multi-omics analysis identifying key biomarkers in ovarian cancer

JY Li, CJ Li, LT Lin, KH Tsui - Cancer Control, 2020 - journals.sagepub.com
Ovarian cancer is one of the most common malignant tumors. Here, we aimed to study the
expression and function of the CREB1 gene in ovarian cancer via the bioinformatic analyses …

[HTML][HTML] Identification of novel biomarkers and candidate drug in ovarian cancer

CJ Li, LT Lin, PY Chu, AJ Chiang, HW Tsai… - Journal of Personalized …, 2021 - mdpi.com
This paper investigates the expression of the CREB1 gene in ovarian cancer (OV) by deeply
excavating the gene information in the multiple databases and the mechanism thereof. In …

Reconstructing differentiation networks and their regulation from time series single-cell expression data

J Ding, BJ Aronow, N Kaminski, J Kitzmiller… - Genome …, 2018 - genome.cshlp.org
Generating detailed and accurate organogenesis models using single-cell RNA-seq data
remains a major challenge. Current methods have relied primarily on the assumption that …

Integrating multiomics longitudinal data to reconstruct networks underlying lung development

J Ding, F Ahangari, CR Espinoza… - … of Physiology-Lung …, 2019 - journals.physiology.org
A comprehensive understanding of the dynamic regulatory networks that govern postnatal
alveolar lung development is still lacking. To construct such a model, we profiled mRNA …

[HTML][HTML] Bioinformatic analyses of canonical pathways of TSPOAP1 and its roles in human diseases

SK Suthar, MM Alam, J Lee, J Monga… - Frontiers in Molecular …, 2021 - frontiersin.org
TSPO-associated protein 1 (TSPOAP1) is a cytoplasmic protein and is closely associated
with its mitochondrial transmembrane protein partner translocator protein (TSPO). To …

CREB1 Transcriptionally Activates LTBR to Promote the NF‐κB Pathway and Apoptosis in Lung Epithelial Cells

Z Hu, G Zhou - Computational and Mathematical Methods in …, 2022 - Wiley Online Library
Bronchopulmonary dysplasia (BPD) is a prevalent chronic pediatric lung disease. Aberrant
proliferation and apoptosis of lung epithelial cells are important in the pathogenesis of BPD …

[HTML][HTML] Kub3 deficiency causes aberrant late embryonic lung development in mice by the FGF signaling pathway

G Yang, S Lu, J Jiang, J Weng, X Zeng - International Journal of …, 2022 - mdpi.com
As a Ku70-binding protein of the KUB family, Kub3 has previously been reported to play a
role in DNA double-strand break repair in human glioblastoma cells in glioblastoma …

Developmental expression of CREB1 and NFATC2 in pig embryos

K Larsen, H Callesen - Molecular Biology Reports, 2023 - Springer
Background The CREB1 gene encodes the cAMP response element binding protein 1
(CREB1), a leucine zipper transcription factor that regulates cellular gene expression in …

Development of the Avian Respiratory System

JN Maina - Current Perspectives on the Functional Design of the …, 2023 - Springer
Comprehensive systematic account of the development of the avian respiratory system,
specifically that of the domestic fowl, Gallus gallus variant domesticus, is presented. Factors …