[HTML][HTML] Efficacy of antiviral therapies for COVID-19: a systematic review of randomized controlled trials

CTR Vegivinti, KW Evanson, H Lyons, I Akosman… - BMC Infectious …, 2022 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) continues to pose a significant
threat to public health worldwide. The purpose of this study was to review current evidence …

[HTML][HTML] Potential therapeutic options for COVID-19: an update on current evidence

Z Niknam, A Jafari, A Golchin, F Danesh Pouya… - European journal of …, 2022 - Springer
Abstract SARS-CoV-2, a novel coronavirus, is the agent responsible for the COVID-19
pandemic and is a major public health concern nowadays. The rapid and global spread of …

[HTML][HTML] Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized, double-blind, placebo-controlled trial

J Vallejos, R Zoni, M Bangher… - BMC infectious …, 2021 - bmcinfectdis.biomedcentral.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has changed our lives. The
scientific community has been investigating re-purposed treatments to prevent disease …

Two years into the COVID-19 pandemic: lessons learned

SJR da Silva, JCF do Nascimento… - ACS infectious …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …

[PDF][PDF] Remdesivir treatment in hospitalized patients with COVID-19: a comparative analysis of in-hospital all-cause mortality in a large multi-center observational …

E Mozaffari, A Chandak, Z Zhang, S Liang… - Clin Infect …, 2021 - scholar.archive.org
Remdesivir treatment in hospitalized patients with COVID-19: a comparative analysis of in-
hospital all-cause mortality in a lar Page 1 © The Author(s) 2021. Published by Oxford University …

[HTML][HTML] Antiviral drug discovery for the treatment of COVID-19 infections

TI Ng, I Correia, J Seagal, DA DeGoey, MR Schrimpf… - Viruses, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), a recently emerged human coronavirus …

[HTML][HTML] Friend or Foe? Implication of the autophagy-lysosome pathway in SARS-CoV-2 infection and COVID-19

W He, Y Gao, J Zhou, Y Shi, D Xia… - International Journal of …, 2022 - ncbi.nlm.nih.gov
There is increasing amount of evidence indicating the close interplays between the
replication cycle of SARS-CoV-2 and the autophagy-lysosome pathway in the host cells …

[HTML][HTML] Therapeutic effectiveness and safety of repurposing drugs for the treatment of COVID-19: position standing in 2021

S Alam, TB Kamal, MMR Sarker, JR Zhou… - Frontiers in …, 2021 - frontiersin.org
COVID-19, transmitted by SARS-CoV-2, is one of the most serious pandemic situations in
the history of mankind, and has already infected a huge population across the globe. This …

[HTML][HTML] Efficacy and safety of remdesivir in hospitalised COVID-19 patients: a systematic review and meta-analysis

MT Angamo, MA Mohammed, GM Peterson - Infection, 2022 - Springer
Purpose This review was aimed to synthesise the best available evidence on the
effectiveness and safety of remdesivir in the treatment of moderate to severe COVID-19 …

Clinical improvement, outcomes, antiviral activity, and costs associated with early treatment with remdesivir for patients with coronavirus disease 2019 (COVID-19)

CKH Wong, KTK Lau, ICH Au, X Xiong… - Clinical Infectious …, 2022 - academic.oup.com
Background Evidence remains inconclusive on any significant benefits of remdesivir in
patients with mild-to-moderate COVID-19. This study explored the disease progression …