Peptidomics and proteomics based on CE‐MS as a robust tool in clinical application: The past, the present, and the future

A Latosinska, J Siwy, H Mischak, M Frantzi - Electrophoresis, 2019 - Wiley Online Library
Capillary electrophoresis combined with mass spectrometry (CE‐MS) has been used for
several years for the investigation of proteins and peptides as biomarkers for diagnosis and …

Towards salivary C-reactive protein as a viable biomarker of systemic inflammation

JB Pay, AM Shaw - Clinical biochemistry, 2019 - Elsevier
C-reactive protein (CRP) is a commonly used marker of systemic inflammation, routinely
measured in serum blood samples. However salivary samples offer a non-invasive and …

Identifying a urinary peptidomics profile for hypertension in young adults: The African‐PREDICT study: Urinary peptidomics and hypertension

D De Beer, CMC Mels, AE Schutte, C Delles… - …, 2023 - Wiley Online Library
Hypertension is one of the most important and complex risk factors for cardiovascular
diseases (CVDs). By using urinary peptidomics analyses, we aimed to identify peptides …

Prediction of coronary artery disease using urinary proteomics

D Wei, JD Melgarejo, L Van Aelst… - European Journal of …, 2023 - academic.oup.com
Aims Coronary artery disease (CAD) is multifactorial, caused by complex pathophysiology,
and contributes to a high burden of mortality worldwide. Urinary proteomic analyses may …

Comparison of urine and plasma peptidome indicates selectivity in renal peptide handling

P Magalhaes, C Pontillo, M Pejchinovski… - PROTEOMICS …, 2018 - Wiley Online Library
Purpose Urine is considered to be produced predominantly as a result of plasma filtration in
the kidney. However, the origin of the native peptides present in urine has never been …

Phenylboronic acid functionalized C3N4 facultative hydrophilic materials for enhanced enrichment of glycopeptides

Y Zhang, H Jing, T Wen, Y Wang, Y Zhao, X Wang… - Talanta, 2019 - Elsevier
It is challenging to capture N-glycopeptides with high recovery and high specificity from
complicated biosystems. Herein, we present a facile and economical procedure to generate …

Proteomics in cardiovascular disease: recent progress and clinical implication and implementation

M Mokou, V Lygirou, A Vlahou… - Expert review of …, 2017 - Taylor & Francis
Introduction: Although multiple efforts have been initiated to shed light into the molecular
mechanisms underlying cardiovascular disease, it still remains one of the major causes of …

L-cysteine functionalized straticulate C3N4 for the selective enrichment of glycopeptides

Y Zhang, H Jing, B Meng, X Qian, W Ying - Journal of chromatography A, 2020 - Elsevier
The facile enrichment of glycopeptides or glycoproteins poses great challenges for
glycoproteomic research. In this study, a novel hydrophilic material, named zwitterionic …

Integrating genes affecting coronary artery disease in functional networks by multi-OMICs approach

B Vilne, H Schunkert - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
Coronary artery disease (CAD) and myocardial infarction (MI) remain among the leading
causes of mortality worldwide, urgently demanding a better understanding of disease …

Utilizing proteomics to understand and define hypertension: where are we and where do we go?

C Delles, E Carrick, D Graham… - Expert Review of …, 2018 - Taylor & Francis
Introduction: Hypertension is a complex and multifactorial cardiovascular disorder. With
different mechanisms contributing to a different extent to an individual's blood pressure, the …